Results 181 to 190 of about 389,527 (304)

Locus-Coeruleus Norepinephrine Functioning as a Predictor of Childhood Mental Health (LOCUS-MENTAL): Protocol for a Longitudinal Study.

JMIR Res Protoc
Todorova I, Neubauer PR, Bast N.
europepmc   +1 more source

Mapping the Interplay Between Childhood Trauma, Substance Use, and Psychopathology in Early Psychosis: A Network Analysis Approach. [PDF]

Schizophr Bull
Kiakos D, Alameda L, Abrahamyan-Empson L, Spanevello C, Gorgellino M, Alerci L, Mebdouhi N, Conus P, Vieira S.   +8 more
europepmc   +1 more source

Distinct Biotypes of Visual Perception in Major Depressive Disorder

Advanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai, Xi‐Wen Hu, Yuyang Li, Zheng Lin, Yongjie Li, Yong‐Chun Cai, Tao Xu, Ke Jia, Jin‐Fang Han, Zhong‐Lin Tan, Dezhong Yao, Xue Mei Song, Sugai Liang, Georg Northoff   +13 more
wiley   +1 more source

The explorer's edge: Racial-ethnic identity exploration confers early adolescents of color with protection against racial-ethnic discrimination in a co-sibling control study. [PDF]

Child Dev
Del Toro J, Aguiling WCL, Dai J, Cheah CSL, Huang Q, Hashim M, Wu B.   +6 more
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Is there an inverted-U relationship between creativity and psychopathology? [PDF]

, 2014
Abraham, AG
core   +2 more sources

Editorial: Global youth mental health crisis: understanding challenges and advancing solutions in psychopathology. [PDF]

Front Psychol
Khalaf A, Gibson RC.
europepmc   +1 more source

PSYCHOPATHOLOGY [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1923
openaire   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Psychopathology. [PDF]

JAMA: The Journal of the American Medical Association, 1922
openaire   +2 more sources