Results 61 to 70 of about 397,654 (297)
BMC Psychiatry, 2021 Background Major depressive disorder (MDD) is a highly prevalent mental disorder with large disease burden, high levels of relapse or persistence, and overall suboptimal outcomes of protocolized pharmacological and psychotherapeutic treatments.
H. Riese +4 more
doaj +1 more source
Phenomenological Psychopathology and Psychiatric Classification [PDF]
, 2019 In this chapter, I provide an overview of phenomenological approaches to psychiatric classification. My aim is to encourage and facilitate philosophical debate over the best ways to classify psychiatric disorders.
Fernandez, Anthony Vincent
core
Schizophrenia, social practices and cultural values: A conceptual introduction [PDF]
, 2018 Schizophrenia is usually described as a fragmentation of subjective experience and the impossibility to engage in meaningful cultural and intersubjective practices. Although the term schizophrenia is less than 100 years old, madness is generally believed
Gonçalves, J. +2 more
core +1 more source
Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif +17 more
wiley +1 more source
On the transience or stability of subthreshold psychopathology
Scientific Reports, 2021 Symptoms of psychopathology lie on a continuum ranging from mental health to psychiatric disorders. Although much research has focused on progression along this continuum, for most individuals, subthreshold symptoms do not escalate into full-blown ...
Marieke J. Schreuder +4 more
doaj +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
iScience, 2023 Summary: Early identification of neurodevelopmental disorders is important to ensure a prompt and effective intervention, thus improving the later outcome.
Caterina Piazza +4 more
doaj +1 more source
Frequency of Parental Psychopathology in Children with Attention Deficit Hyperactivity Disorder [PDF]
, 2012 Parental mental health concerns place children at a significantly greater risk of lower social, psychological and physical health than children in families not affected by mental illness.
Bhat, SM, Latha, KS, Nair, RB
core +1 more source
Predictors of course and outcome in hypochondriasis after cognitive-behavioral treatment [PDF]
, 2002 Background. Predictors of treatment outcome were evaluated in a clinical sample suffering from hypochondriasis. Methods: The sample consisted of 96 patients with hypochondriacal disorder according to DSM-IV or high syndrome scores on the Illness Attitude
Fichter, Manfred M. +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan +46 more
wiley +1 more source