Results 121 to 130 of about 354,339 (315)

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Cycloid Psychosis [PDF]

American Journal of Psychiatry, 2018
Rif S, El-Mallakh, Carolyn, Furdek
openaire   +2 more sources

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota, David J. Grelotti, Tyler Nguyen, Walter H. Kaye, Skylar Swindle, Raymond Suhandynata, Spencer Seely, Megan E. Shott, Guido K. W. Frank   +8 more
wiley   +1 more source

Core beliefs in psychosis: a systematic review and meta-analysis

Schizophrenia
Increasing interest is growing for the identification of psychological mechanisms to account for the influence of trauma on psychosis, with core beliefs being proposed as a putative mediator to account for this relationship.
A. Jorovat, R. Twumasi, A. Mechelli, A. Georgiades   +3 more
doaj   +1 more source

The Impact of Emotion Coaching on Changes in Caregiver Burden and Distress Tolerance During Family‐Based Treatment

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Caregivers often experience elevated stress while supporting a loved one with an eating disorder. This study was a secondary analysis exploring changes in caregiver burden (EDSIS), distress tolerance (DTS), and emotion regulation (ERQ) during family‐based treatment (FBT) among caregivers high in expressed emotion (EE) participating ...
Rachel Kramer, Kimberly Stevens, Megan E. Mikhail, Daniel Le Grange, Anne Shaffer, Claire M. Aarnio‐Peterson   +5 more
wiley   +1 more source

Correction: Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function

Translational Psychiatry, 2021
Paul Allen, Emily J. Hird, Natasza Orlov, Gemma Modinos, Matthijs Bossong, Mathilde Antoniades, Carly Sampson, Matilda Azis, Oliver Howes, James Stone, Jesus Perez, Matthew Broome, Anthony A. Grace, Philip McGuire   +13 more
doaj   +1 more source

Response to clozapine in treatment resistant schizophrenia is related to alterations in regional cerebral blood flow

Schizophrenia
PET and SPECT studies in treatment-resistant schizophrenia (TRS) have revealed significant alterations in regional cerebral blood flow (CBF) during clozapine treatment, which may vary according to the clinical response.
Junyu Sun, Fernando Zelaya, Kyra-Verena Sendt, Grant McQueen, Amy L. Gillespie, John Lally, Oliver D. Howes, Gareth J. Barker, Philip McGuire, James H. MacCabe, Alice Egerton   +10 more
doaj   +1 more source

Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation

BMJ Open
Objectives Providing adequate access to mental health services is a global challenge. Smartphone apps offer a potentially cost-effective, available and accessible solution for monitoring, supporting and treating mental health conditions.
Aljawharah Almuqrin, Ryan Hammoud, Ilham Terbagou, Stefania Tognin, Andrea Mechelli   +4 more
doaj   +1 more source

Deconstructing Psychosis [PDF]

Schizophrenia Bulletin, 2007
Jim, van Os, Carol, Tamminga
openaire   +2 more sources