Results 31 to 40 of about 191,827 (269)

Moderators of treatment effect in a randomised controlled trial of single‐ and multi‐family therapy for anorexia nervosa in adolescents and emerging adults

open access: yesEuropean Eating Disorders Review, EarlyView., 2023
Abstract Introduction Multi‐family therapy for anorexia nervosa (MFT‐AN) is a novel, group‐based intervention that intensifies single‐family therapy for anorexia nervosa (FT‐AN), with the aim of improving outcomes. The current study explored treatment moderators in a randomised controlled trial (N = 167) of FT‐AN and MFT‐AN for young people ...
Julian Baudinet   +5 more
wiley   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang   +7 more
wiley   +1 more source

Exploring patients’ profiles associated with the resolution of acute calcium pyrophosphate arthritis treatedwith colchicine and prednisone: post hoc analysis of a randomized controlled trial

open access: yesArthritis Care &Research, Accepted Article.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart   +14 more
wiley   +1 more source

Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia

open access: yesBJPsych Open, 2017
A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service.
Jessica Foster   +3 more
doaj   +1 more source

Temporal trends in and associations with nonsteroidal anti‐inflammatory drug prescription in adult and pediatric patients with inflammatory bowel disease

open access: yesArthritis Care &Research, Accepted Article.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against NSAID use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal trends in prescription NSAID and ...
Adam S. Mayer   +5 more
wiley   +1 more source

The Implementation and Review of Cognitive Remediation Training for First Episode Psychosis in Singapore

open access: yesFrontiers in Psychiatry, 2021
Objective: Early intervention in patients with first episode psychosis (FEP) can improve cognitive abilities, with both short- and long-term benefits. In this paper, we describe the implementation and review of cognitive remediation training (CRT) in an ...
Nigel Ian Ming Chong   +3 more
doaj   +1 more source

Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐89 with CLBP from 3 VA medical centers underwent baseline testing, randomization to ABC or UC and 12 months follow ...
Debra K. Weiner   +9 more
wiley   +1 more source

Sex Selection Bias in Schizophrenia Antipsychotic Trials—An Update Systematic Review

open access: yesWomen, 2021
The lack of female participation in antipsychotic trials for schizophrenia poses an important issue regarding its applicability, with direct and real-life repercussions to clinical practice. Here, our aim is to systematically review the sampling sex bias
Lais Fonseca   +5 more
doaj   +1 more source

Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

open access: yesAdvanced Science, EarlyView.
This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang   +20 more
wiley   +1 more source

Ten year neurocognitive trajectories in first-episode psychosis

open access: yesFrontiers in Human Neuroscience, 2013
Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant ...
Helene Eidsmo Barder   +27 more
doaj   +1 more source

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