Results 101 to 110 of about 1,450,160 (337)

Overview of psychosocial problems in individuals with stoma: A review of literature

International Wound Journal, 2018
This literature review was conducted to summarise empirical evidence relating to psychosocial health following ostomy surgery during hospitalisation and after discharge.
Sultan Ayaz-Alkaya
semanticscholar   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Family education and support for families at psychosocial risk in Europe: Evidence from a survey of international experts [PDF]

, 2019
First published online: 11 October 2018There is overwhelming consensus among policy makers, academics, and professionals about the need to support families in their childrearing tasks.
Antolín Suárez, Lucía, Hidalgo García, María Victoria, Jiménez García, Lucía, Lorence Lara, Bárbara   +3 more
core   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Optimizing a community-based intervention to improve help-seeking for depression care: study protocol for a randomized factorial trial

Trials
Background Depression is a common mental health issue that can be effectively managed in primary and community health care settings. However, there is a significant gap between the number of individuals in need of care and those who actually receive ...
Nagendra P. Luitel, Brandon A. Kohrt, Bishnu Lamichhane, Anvita Bhardwaj, Kamal Gautam, Mark JD Jordans   +5 more
doaj   +1 more source

The psychosocial impact of assistive device scale: Italian validation in a cohort of nonambulant people with neuromotor disorders [PDF]

, 2018
The importance of adaptive seating system on body structure and function is widely accepted, but its impact on psychosocial aspects needs more consideration by health professionals. This article describes the Italian validation of the Psychosocial Impact
Candeloro, C, Castelli, E, Fabbrini, G, Figura, M, Galeoto, G, Lucibello, L, Sabbadini, M, Tofani, M   +7 more
core   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

EAPC task force on education for psychologists in palliative care [PDF]

, 2010
It is argued that psychological aspects of care and psychosocial problems are essential components of palliative care. However, the provision of appropriate services remains somewhat arbitrary. Unlike medical and nursing care, which are clearly delivered
Costantini, A., Jünger, S., Kalus, C., Payne, Sheila, Werth, J. L.   +4 more
core  

Development and preliminary testing of the psychosocial adjustment to hereditary diseases scale [PDF]

, 2013
Background: The presence of Lynch syndrome (LS) can bring a lifetime of uncertainty to an entire family as members adjust to living with a high lifetime cancer risk.
Cox, Janet E., Dowden, Jeffrey John, Esplen, Mary Jane, Fitzgerald, G. William N., Gregory, Deborah M., LeDrew, Holly M., Ludlow, Valerie C., Parfrey, Patrick S., Watkins, Kathy E., Way, Christine Y.   +9 more
core   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source