Results 91 to 100 of about 400,753 (283)

Pediatric Feeding Disorder: Consensus Definition and Conceptual Framework [PDF]

open access: yes, 2019
Pediatric feeding disorders (PFDs) lack a universally accepted definition. Feeding disorders require comprehensive assessment and treatment of 4 closely related, complementary domains (medical, psychosocial, and feeding skill-based systems and associated
Browne, Joe   +14 more
core   +1 more source

Toward a culturally sensitive conceptualization of resilience: participatory research with war-affected communities in northern Uganda [PDF]

open access: yes, 2015
Resilience research with war-affected populations has long conceptualized resilience as the absence of psychopathology and operationalized it by use of standardized measures.
Ager, Alastair   +4 more
core   +2 more sources

2958 – Achieving Psychosocial Functioning

open access: yesEuropean Psychiatry, 2013
Bipolar disorder is a chronic, severe illness with high rates of relapse, suicide rates, and a remarkable psychosocial burden. Despite the existence of well tested newer drugs that, together with classic mood stabilisers constitute quite a large number of pharmacological treatment options, bipolar patients are symptomatic for almost half their lives.1 ...
openaire   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Psychosocial and adaptive behavior functioning in children following pediatric intensive care unit hospitalization: prospective cohort study

open access: yesBMC Pediatrics
Background With increasing survival rates following pediatric intensive care unit (PICU) hospitalization, assessing functional outcomes is imperative. We compared children’s psychosocial and adaptive functioning six weeks and six months after discharge ...
Reham I. Abdelmageed   +4 more
doaj   +1 more source

Quality of Life and psychopathology in adults who underwent Hematopoietic Stem Cell Transplantation (HSCT) in childhood: a qualitative and quantitative analysis. [PDF]

open access: yes, 2017
Background: Patients who undergo pediatric Hematopoietic Stem Cell Transplantation (HSCT) may experience long-term psychological sequelae and poor Quality of Life (QoL) in adulthood. This study aimed to investigate subjective illness experience, QoL, and
Basso, G.   +13 more
core   +2 more sources

Pathological narcissism and psychosocial functioning.

open access: yesPersonality Disorders: Theory, Research, and Treatment, 2019
Pathological narcissism involves maladaptive efforts to regulate the self and is conceptualized by 2 key features: narcissistic grandiosity and narcissistic vulnerability. Prior research has found that narcissism is associated with poorer functioning over the long term, especially interpersonal functioning.
Samantha C, Dashineau   +3 more
openaire   +2 more sources

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen   +8 more
wiley   +1 more source

Associations between family weight-based teasing, eating pathology, and psychosocial functioning among adolescent military dependents [PDF]

open access: yes, 2019
Weight-based teasing (WBT) by family members is commonly reported among youth and is associated with eating and mood-related psychopathology. Military dependents may be particularly vulnerable to family WBT and its sequelae due to factors associated with
et al,   +2 more
core   +1 more source

Psychoeducational interventions in adolescent depression: A systematic review [PDF]

open access: yes, 2017
Background: Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions.
Bevan Jones, Rhys   +6 more
core   +3 more sources

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