Results 101 to 110 of about 400,753 (283)

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Pragmatic disorders and their social impact [PDF]

, 2011
Pragmatic disorders in children and adults have been the focus of clinical investigations for approximately 40 years. In that time, clinicians and researchers have established a diverse range of pragmatic phenomena that are disrupted in these disorders ...
Cummings, L
core   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Selected aspects of psychosocial functioning of epileptics

Studia Medyczne, 2014
Introduction: Despite advances in medicine, epilepsy remains a mysterious and fearsome disease, which induces social stigma and alienation of those who suffer from it.
Monika Szpringer, Jolanta Karyś, Tomasz Karyś, Ewa Myszkowska, Justyna Kosecka, Bogumił Sobczyk   +5 more
doaj   +1 more source

Nationwide Real‐World Modeling of Surgical Outcomes in Elderly Patients: Incorporating Geriatric‐Specific Risk Factors Into Prediction of Mortality and Morbidity

Annals of Gastroenterological Surgery, EarlyView.
A reliable and effective risk prediction model for mortality and morbidity in elderly patients undergoing gastroenterological surgeries was developed and validated. Geriatric‐specific risk factors, including the newly added variables in the NCD registry, along with age, were identified as significant contributors to the model. ABSTRACT Aim As the aging
Naoya Sato, Hiraku Kumamaru, Mitsukazu Gotoh, Yoshihiro Kakeji, Yuko Kitagawa, Yasuyuki Seto, Hiromi Rakugi, Masahiro Akishita, Kazue Nakajima, Arata Takahashi, Hiroaki Miyata, Shigeru Marubashi   +11 more
wiley   +1 more source

Influences of maternal reflective functioning on adolescents' psychosocial adjustment: The mediating role of adolescent's reflective functioning.

PLoS ONE
This study examines the relationship between maternal reflective functioning and adolescents' reflective functioning and psychosocial adjustment. In Study 1, The Parental Reflective Functioning Questionnaire for Adolescents (PRFQ-A) and Reflective ...
MinKyoung Park, Hyunjoo Song
doaj   +1 more source

Profiles of physical, emotional and psychosocial wellbeing in the Lothian birth cohort 1936 [PDF]

, 2012
Background Physical, emotional, and psychosocial wellbeing are important domains of function. The aims of this study were to explore the existence of separable groups among 70-year olds with scores representing physical function, perceived quality of ...
AE Raftery, AJ Garfein, AJ Gow, AJ Gow, AJ Lamond, AL McCuthcheon, AM Freund, Andrea R Zammit, AS Zigmond, BD Cox, C Depp, C Hertzog, CM Callahan, CR Gale, D Gerstorf, D Nagin, D Wechsler, D Wechsler, DE Schoenfeld, DJ Bauer, DK Mroczek, G Andrews, G Celeux, GJ McLachlan, H Okabayashi, HE Nelson, HS Friedman, Ian J Deary, IJ Deary, IJ Deary, IJ Deary, J Smith, J Smith, John M Starr, JW Rowe, KB DeSalvo, KE Markon, KJ Ko, KR Kruger, L Fratiglioni, L Fratiglioni, L Muthén, LF Berkman, M Lövdén, M Rennemark, MM Baltes, P Townsend, PB Baltes, PB Baltes, PT Costa, S Shiovitz-Ezra, Scottish Council for Research in Education, Scottish Council for Research in Education, ST Charles, V Menec, W Johnson, W Johnson, Wendy Johnson, WHOQOL Group, WJ Strawbridge   +59 more
core   +2 more sources

Delivering a family‐based child mental health promotion program among two resettled refugee communities during the COVID‐19 pandemic: Lessons learned in a hybrid type II implementation‐effectiveness randomized controlled trial

American Journal of Community Psychology, EarlyView.
Abstract Background Resettled refugee families face elevated mental health risks, compounded by structural and cultural barriers. The Family Strengthening Intervention for Resettlement (FSIR), co‐developed with resettled refugee communities, aims to improve family functioning and child mental health.
Euijin Jung, Candace Black, Matias Placencio‐Castro, Lila Chamlagai, Rilwan Osman, Morgan Hoffman, William Beardslee, Theresa S. Betancourt   +7 more
wiley   +1 more source

Risk factors for incidence and persistence of disability in chronic major depression and alcohol use disorders: longitudinal analyses of a population-based study [PDF]

, 2014
BackgroundMajor depression and alcohol use disorders are risk factors for incidence of disability. However, it is still unclear whether a chronic course of these health conditions is also prospectively associated with incidence of disability.
Ayuso-Mateos, J., Caballero, F., Cabello, M., Chatterji, S., Cieza, A.   +4 more
core   +1 more source

Collaborating with transnational families: Learning from the experiences of family caretakers, educators, psychologists, and spiritual leaders in Honduras

American Journal of Community Psychology, EarlyView.
Abstract This manuscript centers on the experiences of caretakers of minors in Honduran transnational families (TNFs) in which one or both parents emigrated, and of the schoolteachers, professional psychologists, and spiritual leaders working with these families.
Marco Gemignani, Yolanda Hernández‐Albújar, Nerea Larrinaga‐Bidegain   +2 more
wiley   +1 more source