Results 121 to 130 of about 24,654 (226)

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study

Addiction, Volume 121, Issue 5, Page 1179-1189, May 2026.
Abstract Aims To describe differences in the expression of genes encoding cannabinoid receptors (CNR1, CNR2), the associated receptor GRP55 and the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGLL) between individuals with alcohol use disorder (AUD) and controls in key mesocorticolimbic brain regions.
María Salud García‐Gutiérrez, Abraham Bailén Torregrosa, Francisco Navarrete, Auxiliadora Aracil‐Fernández, Gabriel Rubio, Jorge Manzanares   +5 more
wiley   +1 more source

Addiction‐related problems in Japan: A regional perspective

Addiction, Volume 121, Issue 5, Page 1316-1324, May 2026.
Abstract Japan's addiction landscape appears paradoxical. The lifetime use of illicit drugs is among the lowest in Organisation for Economic Cooperation and Development countries, but harm from alcohol, tobacco, and gambling ranks among the world's highest.
Soichiro Ide, Yoko Nishitani, Masahiko Sumitani, Masabumi Minami, Tadashi Isa, Masako Iseki, Michiko Ohkura, Hitoshi Okamoto, Tetsuro Kikuchi, Yuko Sekino, Hidehiko Takahashi, Kenji Takeuchi, Atsumi Nitta, Takeshi Honjo, Hiroshi Matsumoto, Tsuyoshi Miyakawa, Toshiya Murai, Toshihiko Matsumoto, Kazuyuki Nakagome, Kazutaka Ikeda   +19 more
wiley   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

British Journal of Pharmacology, Volume 183, Issue 9, Page 2123-2138, May 2026.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner   +2 more
wiley   +1 more source

Once-daily treatment of ADHD with guanfacine: patient implications

Neuropsychiatric Disease and Treatment, 2008
Brandon C StrangeDepartment of Psychiatry at The Ohio State University, Columbus, OH, USAAbstract: The standard of care for treating ADHD is to use a psychostimulant as the first line agent.
Brandon C Strange
doaj  

Astenia en cáncer avanzado y uso de psicoestimulantes [PDF]

, 2011
Asthenia is the most frequent symptom in patients with advanced cancer and is probably what most affects the quality of life of oncology patients since it interferes in their physical and social activity.
Centeno, C. (Carlos), Martínez, M. (Marina), Rubiales, A.S. (A.S.), Tejedor, M.A. (M.A.)   +3 more
core  

Regional cerebellar structural deficits distinguish psychostimulant‐free ADHD youth with and without familial risk for bipolar I disorder: a cross‐sectional morphometric analysis

Journal of Child Psychology and Psychiatry, Volume 67, Issue 5, Page 766-776, May 2026.
Background Although attention‐deficit/hyperactivity disorder (ADHD) with familial risk for bipolar I disorder (BD) may represent a more severe illness conferring greater risk for developing BD, associated neurostructural substrates remain poorly understood.
Biqiu Tang, L. Rodrigo Patino, Wenjing Zhang, Su Lui, Melissa P. DelBello, Robert K. McNamara   +5 more
wiley   +1 more source

Breaking the Chains: Advances in Substance Addiction Research through Single-Cell Sequencing, Epigenetics, and Epitranscriptomic

Future Pharmacology
Addiction is a complex brain disease influenced by genetic, environmental, and neurological factors. Psychostimulants, cocaine, and methamphetamine influence different cell types in different brain regions, with a focus on the neurons responsible for ...
Ana Filošević Vujnović, Ivana Stanković Matić, Lara Saftić Martinović, Sanja Dević Pavlić   +3 more
doaj   +1 more source

Features of oxidative stress markers in mixed saliva of patients with substance use disorders: An observational controlled study

Кубанский научный медицинский вестник
Background. Laboratory monitoring and predicting are potential diagnostic tools for assessing the possible outcome of rehabilitation for patients with substance use disorder.
G. A. Ermakova, E. S. Ustinova, D. A. Lubchenko, A. G. Zavgorodnyaya, I. M. Bykov, K. A. Popov   +5 more
doaj   +1 more source

Using miniscopes and deep learning to compare neurobehavioral representations of psychostimulant and opioid self-administration

Addiction Neuroscience
Concurrent abuse of psychostimulants and opioids represents a growing public health concern. However, preclinical models of substance use disorder often situate psychostimulants and opioids similarly within a unified self-administration procedure.
Matthew C. Broomer, Caroline E. Clark, Jan Shanelle J. Iringan, Michael W. Wang, Nicholas J. Beacher, Da-Ting Lin   +5 more
doaj   +1 more source

Laurate Biosensors Image Brain Neurotransmitters In Vivo: Can an Antihypertensive Medication Alter Psychostimulant Behavior?

Sensors, 2008
Neuromolecular Imaging (NMI) with novel biosensors enables the selective detection of neurotransmitters in vivo within seconds, on line and in real time. Biosensors remain in place for continuing studies over a period of months.
Vivek Murthy, Karyn Wat, Helen Ho, Patricia A. Broderick   +3 more
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