Results 191 to 200 of about 212,785 (310)

Comprehensive exploration of unexplained dyspnoea in subjects with normal ejection fraction and low natriuretic peptides

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 879-887, April 2025.
Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot   +8 more
wiley   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte   +15 more
wiley   +1 more source

Effects of Day‐Patient Treatment on Eating Disorder Symptoms in Persons With Bulimia Nervosa: A Meta‐Analysis

open access: yesEuropean Eating Disorders Review, Volume 34, Issue 4, Page 895-906, July 2026.
ABSTRACT Objective Outpatient treatment for bulimia nervosa (BN) often fails to reduce core symptoms like binge eating and purging, while inpatient care is costly and separates patients from their everyday environment. Day‐patient treatment offers a middle ground by providing intensive daytime therapy with the opportunity to apply skills at home.
Anna L. Dieffenbacher   +2 more
wiley   +1 more source

Faecal Microbiota Transplantation in Anorexia Nervosa: A Systematic Review of Methodologies, Outcomes, and Challenges With Recommendations for Future Studies

open access: yesEuropean Eating Disorders Review, Volume 34, Issue 4, Page 926-945, July 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.
Anna C. Thelen   +6 more
wiley   +1 more source

Associations Between Baseline Severity and Treatment Effects in Digital Interventions for Eating Disorders: A Meta‐Regression

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective While it is assumed that digital interventions are more suitable for milder eating disorder presentations, the evidence supporting this assumption remains unclear. We conducted meta‐regressions testing whether baseline severity at the study level was associated with treatment effects from digital interventions for eating disorders ...
Claudia Liu   +3 more
wiley   +1 more source

Development of the MDMA-Assisted Psychotherapy Side Effects Tool (M-SET): a Delphi study. [PDF]

open access: yesBMJ Open
Colcott J   +12 more
europepmc   +1 more source

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