Results 131 to 140 of about 45,124 (301)

NMDAR‐antibody encephalitis: Seizure semiology and EEG findings

Epileptic Disorders, EarlyView.
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus, Bernard Liem, Sidra Aurangzeb, Mkael Symmonds, Adam E. Handel, Sarosh R. Irani, Arjune Sen   +6 more
wiley   +1 more source

Population profiles of child-reported psychotic-like experiences and their differential association with other psychopathologies

, 2019
Objectives: Childhood psychotic-like experiences (PLEs) increase risk for concurrent and future psychiatric disorders but are common in the population. Strategies are needed to identify vulnerable individuals who may benefit from monitoring or targeted ...
Kristin R. Laurens, Vaughan J. Carr, Dean, K ; https://orcid.org/, Kimberlie Dean, Melissa J. Green, Laurens, KR ; https://orcid.org/, Stacy Tzoumakis, Tzoumakis, S ; https://orcid.org/, Felicity Harris, Tzoumakis, Stacy, Dean, Kimberlie, Harris, Felicity, Carr, Vaughan J, Harris, F ; https://orcid.org/, Green, Melissa J, Carr, VJ ; https://orcid.org/, Green, MJ ; https://orcid.org/, Laurens, Kristin R   +17 more
core   +1 more source

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

Epilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie, Inge M. W. Verberk, Jans S. van Ool, Anneke J. J. Rampen, Rebecca Z. Rousset, Nicole I. Wolf, Dederieke A. M. Maes‐Festen, Clara D. M. van Karnebeek, Charlotte E. Teunissen, Erik Boot, Agnies M. van Eeghen   +10 more
wiley   +1 more source

Psychotic-like experiences in the general population: characterizing a high-risk group for psychosis.

, 2011
Recent research shows that psychotic symptoms, or psychotic-like experiences (PLEs), are reported not only by psychosis patients but also by healthy members of the general population.
Mary Cannon (7895894), Ian Kelleher (7899044), Mary Cannon (480296), Ian Kelleher (480289)   +3 more
core  

Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges

Epilepsia, EarlyView.
Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod, Colin B. Josephson, Samuel Wiebe, The Calgary Comprehensive Epilepsy Program Collaborators, Felippe Borlot, Guillermo Delgado‐García, Paolo Federico, Nathalie Jette, Karl Martin Klein, William Murphy, Neelan Pillay, Andrea Salmon, Shaily Singh, The Epilepsy Surgery Satisfaction Questionnaire Study Group, Mark J. Atkinson, Walter J. Hader, Mark R. Keezer, Oluwaseyi A. Lawal, Sophia Macrodimitris, Kristina Malmgren, Dang K. Nguyen, Scott B. Patten, Tolulope T. Sajobi, Ruby Sharma, Yves Starreveld, José Tellez‐Zenteno, Sandra Wahby   +26 more
wiley   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source

Table_2_Differences Between Self-Reported Psychotic Experiences, Clinically Relevant Psychotic Experiences, and Attenuated Psychotic Symptoms in the General Population.docx

, 2019
Purpose: Psychotic experiences in childhood (such as hearing voices or being suspicious) represent an important phenotype for early intervention. However, these experiences can be defined in several ways: self-reported psychotic experiences (SRPE) rely ...
Luis Augusto Rohde (4813644), Guilherme Vanoni Polanczyk (5694635), Ary Gadelha (291025), Eurípedes Constantino Miguel (7570946), Philip McGuire (325649), Jim van Os (114336), Gisele Gus Manfro (7570943), Jair de Jesus Mari (258064), Tais Silveira Moriyama (7570937), Giovanni Abrahão Salum (7570940), Pedro Mario Pan (4813635), Rodrigo Affonseca Bressan (7504037), Marjan Drukker (555226)   +12 more
core   +1 more source

Long‐term prognosis of pharmacotherapy in newly diagnosed focal epilepsy patients and the predictive value of baseline seizure timing: A prospective cohort study

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun, Shouye Sun, Xinyue Zhang, Weihong Lin   +3 more
wiley   +1 more source

Table_4_Differences Between Self-Reported Psychotic Experiences, Clinically Relevant Psychotic Experiences, and Attenuated Psychotic Symptoms in the General Population.docx

, 2019
Purpose: Psychotic experiences in childhood (such as hearing voices or being suspicious) represent an important phenotype for early intervention. However, these experiences can be defined in several ways: self-reported psychotic experiences (SRPE) rely ...
Luis Augusto Rohde (4813644), Guilherme Vanoni Polanczyk (5694635), Ary Gadelha (291025), Eurípedes Constantino Miguel (7570946), Philip McGuire (325649), Jim van Os (114336), Gisele Gus Manfro (7570943), Jair de Jesus Mari (258064), Tais Silveira Moriyama (7570937), Giovanni Abrahão Salum (7570940), Pedro Mario Pan (4813635), Rodrigo Affonseca Bressan (7504037), Marjan Drukker (555226)   +12 more
core   +1 more source

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal, Patrick Landazuri, David E. Burdette, Sanjay Patra, Angela N. Crudele, Dario Englot, Jay R. Gavvala, Sandipan Pati, Lesley C. Kaye, Steven Ojemann, Daniel Barnett, Joseph Neimat, Adriana E. Palade, Shervin Rahimpour, Amir A. Arain, Robert Mark Richardson, Sydney S. Cash, Vicenta Salanova, Alexandra Urban, William P. Welch, Jamie Joseph Van Gompel, Keith Starnes, David Spencer, Lia D. Ernst, Ushtar Amin, Angelica Rivera‐Cruz, Patricia Dugan, Marytery Fajardo, Matt Lallas, Barbara C. Jobst, Nicole Odom, Jarod L. Roland, Jon T. Willie, Sameer A. Sheth, Alica M. Goldman, Christopher T. Skidmore, Chengyuan Wu, Cornelia Drees, Jonathon Parker, Taneeta Mindy Ganguly, Jerzy Szaflarski, Saadi Ghatan, Lise Johnson, Jacob Norman, Brett Wingeier, Cairn G. Seale, Martha J. Morrell, Nautilus Study Group   +47 more
wiley   +1 more source