Results 91 to 100 of about 1,392,533 (259)

Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi, Céline Louveau, Bertrand Diebold, Natacha Gaitch, Arnaud Hubas, Martine Gautier Vallee, Jérôme Champ, Anais L'Haridon, Sophie Georgin Lavialle, Boris Chaumette, Thierry Bienvenu   +10 more
wiley   +1 more source

Multi-domain destructuring in the early phases of psychosis: a multicentric phenomenological and psychometric case-control study

Frontiers in Behavioral Neuroscience
IntroductionThe study aims to evaluate symptomatic differences through psychometric tools comparing patients in the early stages of psychotic development with those exhibiting a more established symptomatology.
Ottone Baccaredda Boy, Ottone Baccaredda Boy, Giuseppe Pierpaolo Merola, Andrea Patti, Andrea Patti, Bernardo Bozza, Dario Flaccomio, Marco Faldi, Giulia Pitt, Luca Papini, Vincenzo Pecoraro, Ilaria Noschese, Ilaria Noschese, Elisa Di Matteo, Dario Brugnolo, Camilla Ricci, Camilla Ricci, Andrea Ballerini, Francesco Mauceri, Francesco Mauceri, Simone Tavano, Simone Tavano, Giulio Peroni, Giulio Peroni, Sara Ciabattini, Sara Ciabattini, Sara Gori, Tiziana Pisano, Francesco De Cesaris, David Cohen, Valdo Ricca   +30 more
doaj   +1 more source

Schizophrenia, Not a Psychotic Disorder: Bleuler Revisited

Frontiers in Psychiatry, 2019
Current diagnostic criteria delineate schizophrenia as a discrete entity essentially defined by positive symptoms. However, the role of positive symptoms in psychiatry is being questioned.
Alexandre Andrade Loch, Alexandre Andrade Loch   +1 more
doaj   +1 more source

Toward a Behavioral Reserve Model in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Behavioral impairment is common in amyotrophic lateral sclerosis (ALS) and strongly affects autonomy, caregiver burden, and outcomes, yet predictors of vulnerability remain unclear. We investigated whether premorbid regulatory traits and socio‐educational exposures are associated with behavioral phenotypes in ALS within a behavioral reserve ...
Francesca Palumbo, Barbara Iazzolino, Cristina Moglia, Umberto Manera, Enrico Matteoni, Sara Cabras, Giorgio Pellegrino, Emilio Minerva, Vita Passidomo, Rosario Vasta, Gabriele Mora, Fabrizio D’Ovidio, Antonio Canosa, Andrea Calvo, Adriano Chiò   +14 more
wiley   +1 more source

Prevalence and risk factors for psychotic symptoms in young, first-episode and drug-naïve patients with major depressive disorder

BMC Psychiatry
Background Major depressive disorder (MDD) is a common psychiatric disorder worldwide. Psychotic depression has been reported to be frequently under-diagnosed due to poor recognition of psychotic features.
Yuxuan Wu, Xueli Zhao, Zhe Li, Ruchang Yang, Ruijie Peng, Yue Zhou, Xingzhi Xia, Hanxu Deng, Xiaobin Zhang, Xiangdong Du, Xiangyang Zhang   +10 more
doaj   +1 more source

Association of clinical variables and thyroid-stimulating hormone with psychotic symptoms in patients with first-episode and drug-naïve major depressive disorder with elevated fasting blood glucose: preliminary exploratory study with a large sample

BJPsych Open
Background Psychotic symptoms and elevated fasting blood glucose (FBG) are frequently observed in people with major depressive disorder (MDD), but there is a lack of research into this relationship within this cohort.
Qian Yang, Qianjin Wang, Pu Peng, Tieqiao Liu, Xiangyang Zhang   +4 more
doaj   +1 more source

Cortical Thickness and White Matter Surface Morphology in Tourette Syndrome: A Cohort Study

Annals of Neurology, EarlyView.
Objective To examine cortical thickness and white matter surface morphology in a large sample of individuals with Tourette syndrome (TS) and neurotypical controls across the lifespan, and to assess associations with symptom severity, comorbidities, and medication use.
Sahar Delavari, Adam C. Frank, Ravi Bansal, Flora M. Vaccarino, Robert A. King, Paul Lombroso, Lawrence Scahill, James F. Leckman, Bradley S. Peterson   +8 more
wiley   +1 more source

Hyperostosis frontalis interna: Observed patterns, prevalence, and dementia associations in older adults

The Anatomical Record, EarlyView.
Abstract Hyperostosis frontalis interna (HFI) is a frequently underrecognized condition characterized by overgrowth of the frontal endocranium, most commonly observed in post‐menopausal women. Although its etiology remains unclear, hormonal influences and a possible relationship with neurocognitive changes have been proposed.
Danielle Felsberg, Kira Morgan, Rickey‐Levon Burch, Madelyn Furr, Zachary Tyson, Steven Lesh   +5 more
wiley   +1 more source

The triglyceride-glucose index in relation to psychotic symptoms in adolescents with major depressive disorder

Frontiers in Psychiatry
ObjectiveIt is increasingly recognized that insulin resistance (IR) is associated with major depressive disorder(MDD) and a spectrum of psychotic symptoms.
Yi Tang, Wen Wu, Yun Zhang, Ji Yin, Dan Luo, Zhangyan Zhou, Hansong Xu   +6 more
doaj   +1 more source

Emotion Regulation Difficulties in Autism‐PTSD Co‐Occurrence

Autism Research, EarlyView.
ABSTRACT Autistic individuals face an increased risk of experiencing traumatic events and of being significantly affected by them, whether these events are life‐threatening or social in nature. Emotion regulation (ER) difficulties are central to both conditions, yet their role in this neuropsychiatric co‐occurrence remains under‐researched.
Eldar Fayena, Shir Shaked‐Ashkenazi, Michal Shoval, Mordi Benhamou, Nathaniel Laor, Danny Horesh, Ofer Golan   +6 more
wiley   +1 more source