Results 131 to 140 of about 126,270 (309)

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie   +10 more
wiley   +1 more source

Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges

open access: yesEpilepsia, EarlyView.
Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod   +26 more
wiley   +1 more source

Thinking about thinking: an exploration of metacognitive factors in the development and maintenance of positive psychotic symptoms

open access: yes, 2013
The literature review discusses the role of metacognition, defined as the cognitive processes involved in ‘thinking about thinking’, in the development and maintenance of persecutory delusions and auditory hallucinations. Much of the literature points to
Norman, Catherine
core  

Long‐term prognosis of pharmacotherapy in newly diagnosed focal epilepsy patients and the predictive value of baseline seizure timing: A prospective cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun   +3 more
wiley   +1 more source

Psychotic-like experiences and correlation with distress and depressive symptoms in a community sample of adolescents and young adults

open access: yes, 2010
Psychotic-like experiences and correlation with distress and depressive symptoms in a community sample of adolescents and young ...
M Birchwood (12746618)   +6 more
core  

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini   +9 more
wiley   +1 more source

Association between triglyceride glucose index (TyG) and psychotic symptoms in patients with first-episode drug-naïve major depressive disorder

open access: yesFrontiers in Psychiatry
ObjectiveMajor depressive disorder (MDD) sufferers frequently have psychotic symptoms, yet the underlying triggers remain elusive. Prior research suggests a link between insulin resistance (IR) and increased occurrence of psychotic symptoms.
Junjun Liu   +15 more
doaj   +1 more source

Spike detection in the wild: Screening of suspected temporal lobe epilepsy cases using a tailored 2‐channel wearable EEG

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To clinically validate the contribution of a custom‐built EEG wearable device (waEEG) compared to a full 10–20 electrode array ambulatory EEG (aEEG) for screening epilepsy cases in patients with suspected temporal lobe epilepsy (TLE) but negative routine EEGs. Methods Patients (aged 16–91 years) with clinically suspected TLE who were
Daniel Filipe Borges   +4 more
wiley   +1 more source

Exploring the Nature and Function of Religious Beliefs in Psychosis: A Case Study Approach

open access: yes, 2010
This study investigated the potential developmental, maintaining, or protective role of religious beliefs in the presentation of psychotic symptoms.
Lenny, Megan
core  

Long‐Term Effectiveness of Inpatient and Day‐Hospital Treatment of Eating Disorders in Departments of Psychosomatic Medicine and Psychotherapy in Germany

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background There is ample evidence on the efficacy of different therapeutic approaches in treating eating disorders. Yet, studies on the effectiveness of inpatient/day‐hospital treatment of eating disorders are rare. Method Data were retrieved from a naturalistic multi‐center effectiveness study of inpatient and day‐hospital treatment in ...
Magdalena Pape   +42 more
wiley   +1 more source

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