Results 91 to 100 of about 52,275 (325)
Drug Recommendation toward Safe Polypharmacy [PDF]
arXiv, 2018 Adverse drug reactions (ADRs) induced from high-order drug-drug interactions (DDIs) due to polypharmacy represent a significant public health problem. In this paper, we formally formulate the to-avoid and safe (with respect to ADRs) drug recommendation problems when multiple drugs have been taken simultaneously.
arxiv
Drug Testing and Analysis, EarlyView.The new ionization technique, vacuum‐insulated probe‐heated electrospray, allows for a simple dilute‐and‐shoot sample preparation to be used with liquid chromatography time‐of‐flight mass spectrometry in urine drug screening. Comparison with a method relying on solid‐phase extraction and conventional electrospray ionization shows improved performance ...
Mira Sundström +4 more
wiley +1 more source
Deprescribing psychotropic drugs in a geriatric psychiatry outpatient clinic
Geriatrics, Gerontology and AgingObjective: To describe the psychotropic drug deprescription process in older patients of a geriatric psychiatry outpatient clinic. Methods: We conducted a quasi-experimental study of people aged < 60 years who were treated at Hospital São Lucas ...
Natascha Melo Linkievicz +4 more
doaj +1 more source
High prevalence of prescription of psychotropic drugs for older patients in a general hospital
BMC Pharmacology and Toxicology, 2017 Background Many elderly patients receive psychotropic drugs. Treatment with psychotropic agents is associated with serious side effects including an increased risk of falls and fractures.
Inken Arnold +7 more
doaj +1 more source
On the Way to More Convenient Description of Drug-Plasma Protein Binding [PDF]
arXiv, 2012 The theoretical case is considered where the total amount of plasma protein is conserved, but the drug is eliminated after its single application. After a single drug application at time t = 0, the total drug concentration is measured at times ti,...,tk and the total drug concentration at time ti is denoted by {\phi}i.
arxiv
On the metapharmacology of psychotropic drugs
Comprehensive Psychiatry, 1965 Summary We have proposed psychoanalytic metapsychology as a useful explanatory tool for investigation of drug effects upon the psychic apparatus. All six metapsychological points of view: (1) genetic; (2) dynamic; (3) topographic; (4) structural; (5) economic; (6) adaptive, were brought to bear upon the psychic events in connection with drug use ...
Roy M. Whitman, Paul H. Ornstein
openaire +3 more sources
Drug Testing and Analysis, EarlyView.Microbial biotransformation and stability of deschloroketamine derivatives and their metabolites in WW by incubating parent compounds, rat urine, or rat feces showed that deschloroketamine parents and Phase I metabolite were still detectable and that Phase II metabolites decreased in peak areas.
Fabian Frankenfeld +2 more
wiley +1 more source
Precision Medical Sciences, Volume 11, Issue 4, Page 186-194, December 2022., 2022 Voriconazole injection of Hailing Pharmaceutical Group has achieved a breakthrough in improving the solubility of voriconazole with different excipients for the first time in China. We evaluated the pharmacokinetics (PK) and safety of single/multiple doses of voriconazole injection of Hailing Pharmaceutical Group (Test, T), a biosimilar to Vfend ...
Chunqi Huang +15 more
wiley +1 more source
Analysis of psychotropic drug-related deaths in south Osaka
Substance Abuse and Rehabilitation, 2018 Naoto Tani,1,2 Tomoya Ikeda,1,2 Tomomi Michiue,1,2 Shigeki Oritani,1 Fumiya Morioka,1 Takaki Ishikawa1,2 1Department of Legal Medicine, Osaka City University Medical School, Abeno, Osaka, Japan; 2Forensic Autopsy Section, Medico-legal Consultation and ...
Tani N +5 more
doaj
BMC Family Practice, 2019 Background The prescribing of psychotropic drugs, i.e. antidepressants, sedatives (anxiolytics, hypnotics), and antipsychotics is considerable and a large proportion is prescribed by general practitioners (GPs).
Staffan A. Svensson +2 more
doaj +1 more source