Results 21 to 30 of about 52,275 (325)

Dissecting the novel abilities of aripiprazole: The generation of anti-colorectal cancer effects by targeting Gαq via HTR2B

open access: yesActa Pharmaceutica Sinica B, 2023
Colorectal cancer (CRC) is a type of malignant tumor that seriously threatens human health and life, and its treatment has always been a difficulty and hotspot in research.
Haowei Liu   +5 more
doaj  

A Retrospective Study of the Effects of Psychotropic Drugs on Neuroendocrine Hormones in Patients with Bipolar Disorder

open access: yesNeuropsychiatric Disease and Treatment, 2021
Shengnan Zhao, Bo Zhang, Xueli Sun Mental Health Center, West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Xueli SunMental Health Center, West China Hospital of Sichuan University, Chengdu ...
Zhao S, Zhang B, Sun X
doaj  

Use of Psychotropic Medications and Illegal Drugs, and Related Consequences Among French Pharmacy Students – SCEP Study: A Nationwide Cross-Sectional Study

open access: yesFrontiers in Pharmacology, 2018
Background: The use of psychotropic medications and illegal drugs is a worldwide public health issue, leading to addiction, psychiatric and somatic disorders, and death.
David Balayssac   +7 more
doaj   +1 more source

Analise Demografica e Socioeconomica do Uso e do Acesso a Medicamentos Antidepressivos no Brasil [PDF]

open access: yesarXiv, 2021
Depressive disorders, in addition to causing direct negative impacts on health, are also responsible for imposing substantial costs on society. In relation to the treatment of depression, antidepressants have proven effective, and, to the World Health Organization, access to psychotropic drugs for people with mental illnesses offers a chance of ...
arxiv  

Drug Selection via Joint Push and Learning to Rank [PDF]

open access: yesIEEE/ACM Transactions on Computational Biology and Bioinformatics ( Volume: 17, Issue: 1, 01 Jan.-Feb. 2020), 2018
Selecting the right drugs for the right patients is a primary goal of precision medicine. In this manuscript, we consider the problem of cancer drug selection in a learning-to-rank framework. We have formulated the cancer drug selection problem as to accurately predicting 1). the ranking positions of sensitive drugs and 2).
arxiv   +1 more source

Socioeconomic determinants of psychotropic drug utilisation among elderly: a national population-based cross-sectional study

open access: yesBMC Public Health, 2010
Background Psychotropic drugs are commonly utilised among the elderly. This study aimed to analyse whether two socioeconomic determinants - income and marital status - are associated with differences in utilisation of psychotropic drugs and potentially ...
Petzold Max   +3 more
doaj   +1 more source

Hyperbolic Molecular Representation Learning for Drug Repositioning [PDF]

open access: yesarXiv, 2022
Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target are grouped together.
arxiv  

Depression and anxiety in Hodgkin lymphoma patients: A Danish nationwide cohort study of 945 patients

open access: yesCancer Medicine, 2020
Cancer‐related psychological distress may lead to depression and anxiety among survivors. The vast majority of patients with Hodgkin lymphoma (HL) become long‐term survivors, but the risk of mental health problems after HL is not well‐characterized ...
Andreas K. Øvlisen   +11 more
doaj   +1 more source

AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]

open access: yesarXiv, 2023
Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv  

NeuroCADR: Drug Repurposing to Reveal Novel Anti-Epileptic Drug Candidates Through an Integrated Computational Approach [PDF]

open access: yesarXiv, 2023
Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and less failure prone than drugs developed from traditional methods.
arxiv  

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