Results 61 to 70 of about 52,275 (325)
Al-Mustansiriyah Journal of Pharmaceutical SciencesBackground: Clinically significant drug-drug interactions can be defined as events in which the pharmacodynamics or pharmacokinetic characteristics of a drug are modified by coadministration of a second drug to the patient’s medication protocol, which ...
Raz Muhammed HamaSalih +4 more
doaj +1 more source
New method for the study of psychotropic drug effects under simulated clinical conditions [PDF]
arXiv, 2007 The sensory contact model allows forming different psychopathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, hypersensitivity, cognition disturbances, anhedonia, alcoholism etc.) produced by repeated agonistic interactions in male mice and investigating the therapeutic and preventive properties of any drug as
arxiv
Graph Distance Neural Networks for Predicting Multiple Drug Interactions [PDF]
arXiv, 2022 Since multidrug combination is widely applied, the accurate prediction of drug-drug interaction (DDI) is becoming more and more critical. In our method, we use graph to represent drug-drug interaction: nodes represent drug; edges represent drug-drug interactions.
arxiv
Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 449-456, December 2022., 2022 Abstract Aim It is controversial whether psychotic features are a risk factor for relapse in patients with electroconvulsive therapy‐responsive major depressive disorder. A recent study reported that benzodiazepine receptor agonists reduce relapse of psychotic depression.
Akise Umakoshi +7 more
wiley +1 more source
Use of psychotropic drugs among Indigenous and Quilombola communities in Brazil
Salud ColectivaThe use of psychotropic drugs has become a public health issue due to their high consumption worldwide. In the context of traditional populations, the literature on the use of these medications is scarce.
Gabriela da Silva Gonçalves Loures +7 more
doaj +1 more source
Drug-target affinity prediction method based on consistent expression of heterogeneous data [PDF]
arXiv, 2022 The first step in drug discovery is finding drug molecule moieties with medicinal activity against specific targets. Therefore, it is crucial to investigate the interaction between drug-target proteins and small chemical molecules. However, traditional experimental methods for discovering potential small drug molecules are labor-intensive and time ...
arxiv
In Vitro Psilocybin Synthesis by Co‐Immobilized Enzymes
Chemistry – A European Journal, EarlyView.The drug candidate and psychedelic mushroom product psilocybin was produced by multienzyme‐charged beads in a biocatalytic cell‐free approach. Using immobilized fungal indolethylamine biosynthetic and additional bacterial enzymes, these beads turned over 4‐hydroxy‐l‐tryptophan to psilocybin.
Tim Schäfer +7 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 410-420, December 2022., 2022 Three studies comparing quetiapine with lithium were identified and analyzed; no other antipsychotic‐mood stabilizer combinations were found. Although this study found no differences in the efficacy and safety of quetiapine and lithium for bipolar depression, a comprehensive comparison of antipsychotics and mood stabilizers was not performed.
Masaya Ogasawara +8 more
wiley +1 more source
A Drug Utilization Study of Psychotropic Drugs Prescribed in the Psychiatry Outpatient Department of a Tertiary Care Hospital [PDF]
Journal of Clinical and Diagnostic Research, 2013 Background: Psychiatric disorders are one of the major causes of morbidity. Development of newer drugs like SSRIs and atypical antipsychotics has altered the treatment paradigms. Various factors like cost of drugs, local paradigms, etc. play a role in
Karan B. Thakkar +4 more
doaj +1 more source
Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 421-429, December 2022., 2022 Abstract Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the glutamatergic system.
Ahmad Shamabadi
wiley +1 more source