Results 81 to 90 of about 52,275 (325)

A preliminary study on predictors of treatment response to repetitive transcranial magnetic stimulation in patients with treatment‐resistant depression in Japan

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 478-484, December 2022., 2022
Abstract Background Brain imaging studies have reported that the effect of repetitive transcranial magnetic stimulation (rTMS) is associated with the activities of the dorsolateral prefrontal cortex (DLPFC) and ventral medial prefrontal cortex (VMPFC). However, few studies have been conducted in Japanese patients. Aim We aimed to identify brain regions
Haruki Ikawa, Mamoru Tochigi, Yoshihiro Noda, Hiroshi Oba, Tatsuro Kaminaga, Keita Sakurai, Emi Ikebuchi, Naoki Hayashi, Hiroshi Kunugi   +8 more
wiley   +1 more source

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

Drug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman, Marie H. Deventer, Rachael Andrews, Robert Reid, Victoria Marland, Darren Edwards, Christopher R. Pudney, Niamh Nic Daéid, Christophe P. Stove, Caitlyn Norman   +9 more
wiley   +1 more source

Development of individual fitness score for conformity of prescriptions to the “Guidelines For Pharmacological Therapy of Schizophrenia”

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 502-509, December 2022., 2022
Abstract Aims The Guidelines for the Pharmacotherapy of Schizophrenia were established to improve the quality of medical care, and the EGUIDE project was conducted to train clinicians on guideline usage. A quality indicator (QI) was established to measure the prevalence of the guidelines, and a survey was conducted, which revealed a gap between the ...
Ken Inada, Kentaro Fukumoto, Naomi Hasegawa, Yuka Yasuda, Hisashi Yamada, Hikaru Hori, Kayo Ichihashi, Hitoshi Iida, Kazutaka Ohi, Hiroyuki Muraoka, Fumitoshi Kodaka, Kenta Ide, Naoki Hashimoto, Jun‐ichi Iga, Kazuyoshi Ogasawara, Kiyokazu Atake, Yoshikazu Takaesu, Tatsuya Nagasawa, Hiroshi Komatsu, Tsuyoshi Okada, Ryuji Furihata, Mikio Kido, Saya Kikuchi, Chika Kubota, Manabu Makinodan, Shinichiro Ochi, Masahiro Takeshima, Hirotaka Yamagata, Junya Matsumoto, Kenichiro Miura, Masahide Usami, Taishiro Kishimoto, Toshiaki Onitsuka, Eiichi Katsumoto, Akitoyo Hishimoto, Shusuke Numata, Norio Yasui‐Furukori, Koichiro Watanabe, Ryota Hashimoto   +38 more
wiley   +1 more source

Concomitant prescription of psychotropic and cardiovascular drugs in elderly patients

Psychiatry and Clinical Psychopharmacology, 2017
OBJECTIVES: Cardiovascular disorders and medication are highly prevalent in elderly. Due to age-related changes, the elderly are particularly vulnerable to side effects and adverse drug reactions.
Zeynep Ozturk, Ayse Turkyilmaz
doaj   +1 more source

Drug-drug interaction prediction based on co-medication patterns and graph matching [PDF]

arXiv, 2019
Background: The problem of predicting whether a drug combination of arbitrary orders is likely to induce adverse drug reactions is considered in this manuscript. Methods: Novel kernels over drug combinations of arbitrary orders are developed within support vector machines for the prediction.
arxiv  

Associations Between Self‐Reported Cocaine Use Patterns and Cocaine and Its Metabolites in Hair: Implications for Clinical and Forensic Practices

Drug Testing and Analysis, EarlyView.
This study demonstrates that concentrations of cocaine and its main metabolites in hair reliably predict an individual's actual intensity of cocaine use and effectively differentiate between dependent and non‐dependent users. ABSTRACT In forensic toxicology, it has been debated if hair testing allows an estimation of the intensity of cocaine use—an ...
Simon Grison, Lydia Johnson‐Ferguson, Matthias Vonmoos, Markus R. Baumgartner, Boris B. Quednow   +4 more
wiley   +1 more source

Association between functional recovery and medication adherence in schizophrenia

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 510-515, December 2022., 2022
Abstract Aim Medication adherence is important for achieving functional recovery from schizophrenia and is commonly assessed using the Drug Attitude Inventory‐30 (DAI‐30). Subscales of the DAI‐30, including “awareness of the need for medication,” “awareness of the effects of psychiatric drugs,” and “impression of medication,” have been used to assess ...
Junpei Ishii, Fumitoshi Kodaka, Hisatsugu Miyata, Wataru Yamadera, Hikaru Seto, Hidejiro Higuchi, Yoshiaki Tsuruoka, Masahiro Shigeta   +7 more
wiley   +1 more source

Consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients

BMC Geriatrics, 2019
Background Dementia patients often show neuropsychiatric symptoms, known as behavioral and psychological symptoms of dementia (BPSD). These are a common motive for medical consultations, hospitalizations, and nursing home stays.
Mireia Massot Mesquida, Montserrat Tristany Casas, Alicia Franzi Sisó, Isabel García Muñoz, Óscar Hernández Vian, Pere Torán Monserrat   +5 more
doaj   +1 more source

Analytical and Pharmacological Characterization of 1‐(Furan‐2‐Carbonyl)‐LSD (1F‐LSD) and Comparison With 1‐(Thiophene‐2‐Carbonyl)‐LSD (1T‐LSD)

Drug Testing and Analysis, EarlyView.
The novel lysergamide 1‐(furan‐2‐carbonyl)‐LSD (1F‐LSD) was analytically characterized. 1F‐LSD showed LSD‐like activity in vivo similar to 1‐(thiophene‐2‐carbonyl)‐LSD (1T‐LSD) used for comparison. Administration studies in mice and LC–MS analysis revealed that 1F‐LSD served as a prodrug.
Simon D. Brandt, Pierce V. Kavanagh, Sarah Gare, Simon P. Elliott, Alexander Stratford, Adam L. Halberstadt   +5 more
wiley   +1 more source

A reliable quantitative method for determining CBD content and release from transdermal patches in Franz cells

Phytochemical Analysis, Volume 33, Issue 8, Page 1257-1265, December 2022., 2022
Abstract Introduction There are several cannabidiol (CBD) transdermal patches available on the market. However, none are FDA‐approved. Furthermore, not much evidence has been published about CBD release and skin permeation from such patches, so the effectiveness and reliability remain unclear. Objectives We aimed to develop a method to determine the in
Liyun Yu, Frederikke Bahrt Madsen, Sofie Helvig Eriksen, Aaron J. C. Andersen, Anne Ladegaard Skov   +4 more
wiley   +1 more source