Results 111 to 120 of about 6,622,332 (365)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

SARS-CoV-2 Infection-Dependent Modulation in Vital Components of the Serum Profile of Severely SARS-CoV-2 Infected Patients

open access: yesInfection and Drug Resistance
Mohammad Asrar Izhari Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha, Saudi ArabiaCorrespondence: Mohammad Asrar Izhari, Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Al-Baha ...
Izhari MA
doaj  

Dual PT-Symmetric Quantum Field Theories

open access: yes, 2005
Some quantum field theories described by non-Hermitian Hamiltonians are investigated. It is shown that for the case of a free fermion field theory with a $\gamma_5$ mass term the Hamiltonian is $\cal PT$-symmetric.
Abdalla   +18 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Haemostatic Abnormalities in Patients with Cirrhosis and their Relation with Severity of Liver Dysfunction as Assessed by Child Pugh Score

open access: yesJLUMHS, 2017
OBJECTIVE: To evaluate the hemostatic abnormalities in patients with cirrhosis and their relation with severity of liver dysfunction as assessed by Child Pugh Score.
Hanozia Hassan   +2 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Thermally stable single atom Pt/m-Al2O3 for selective hydrogenation and CO oxidation

open access: yesNature Communications, 2017
Single-atom metal catalysts offer a promising way to utilize precious noble metal elements more effectively, provided that they are catalytically active and sufficiently stable.
Zailei Zhang   +10 more
semanticscholar   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Physiotherapists’ Attitudes, and Barriers of Delivering Cardiopulmonary Rehabilitation for Patients with Heart Failure in Saudi Arabia: A Cross-Sectional Study

open access: yesJournal of Multidisciplinary Healthcare, 2022
Abdulelah M Aldhahir,1,* Munyra Alhotye,2,* Jaber S Alqahtani,3 Ibrahim A AlDraiwiesh,3 Saeed M Alghamdi,4,5 Abdullah S Alsulayyim,1,5 Abdullah A Alqarni,6 Shahad K Khormi,6 Eidan M Alzahrani,7 Ahmed M Al Rajeh,8 Yousef S Aldabayan,8 Rayan A ...
Aldhahir AM   +16 more
doaj  

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