Results 51 to 60 of about 161,469 (302)

How Does Wind Project Performance Change with Age in the United States? [PDF]

, 2020
Wind-plant performance declines with age, and the rate of decline varies between regions. The rate of performance decline is important when determining wind-plant financial viability and expected lifetime generation.
Bolinger, M, Hamilton, SD, Jeong, S, Millstein, D, Wiser, R   +4 more
core  

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Intelligence quotient scores among early-treated phenylketonuria patients: results from a systematic literature review

Orphanet Journal of Rare Diseases
Background Phenylketonuria (PKU) is a rare condition that causes the accumulation of phenylalanine; without prompt diagnosis and treatment following birth, severe neurologic and cognitive impairments occur.
Fiona O’Sullivan, Ioannis Tomazos, Francjan J. van Spronsen, Shelagh M. Szabo, Maanasa Venkataraman, Lavanya Huria, Neil Smith, Lachlan Molony, Kim Ingalls, Kathleen Somera-Molina, Rongrong Zhang, Cary O. Harding   +11 more
doaj   +1 more source

Electroactive Metal–Organic Frameworks for Electrocatalysis

Advanced Functional Materials, EarlyView.
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska, Yutong Luo, Ruyan Zhao, Jianjun Zhang, Mingchao Wang, Xinliang Feng, Eike Brunner, Stefan Kaskel   +7 more
wiley   +1 more source

Ethnic Bridging of Sepiapterin in Chinese and Korean Populations Based on Predictions From Genetic Polymorphism of Breast Cancer Resistance Protein

Clinical and Translational Science
Ethnic differences are crucial when considering the efficacy, safety, and dose of pharmaceuticals across diverse populations. The International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) guideline E5 ...
Lan Gao, Neil Smith, Ronald Kong
doaj   +1 more source

Fibrinogen-to-Neutrophil Ratio as a New Predictor of Central Lymph Node Metastasis in Patients with Papillary Thyroid Cancer and Type 2 Diabetes Mellitus

Cancer Management and Research, 2022
Danni Zheng,1 Jiawen Yang,2 Jiali Qian,2 Lingli Jin,1 Guanli Huang3,4 1Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Wenzhou Medical University, Wenzhou ...
Zheng D, Yang J, Qian J, Jin L, Huang G
doaj  

Theoretical and Experimental Study for the Effect of Mass Flow Rate and concentration ratio of PTC Close Type Solar Collector in Kirkuk City [PDF]

Kirkuk Journal of Science, 2017
Theoretical and experimental study has been used to analysis close type solar collector PTC in south of Kirkuk city in Iraq 43°.53" longitude, 35°.25" width with elevation of 217 m. The mass flow rate of water and concentration ratio are (0.00083, 0.0011,
Ahmad H. Ahmad, Ahmad S.Mohammad, Hussain S. Akbar   +2 more
doaj   +1 more source

4D‐Printed Magneto‐Plasmonic Microrobots for Programmable Spatiotemporal De‐Icing

Advanced Functional Materials, EarlyView.
A 4D‐printing strategy is introduced to achieve programmable de‐icing devices. By aligning gold–magnetite nanofillers within a photosensitive resin, the printed structures exhibit dual magnetic and plasmonic functionalities, enabling precise spatio‐temporal ice removal through thermoplasmonic effects.
Amélie Pérot, Andrea Cosola, Eléonore Aïdonidis, Jérôme Fresnais, Clément Sanchez, Philippe Belleville, Giancarlo Rizza, Marco Faustini   +7 more
wiley   +1 more source

Position of Premature Termination Codons Determines Susceptibility of hERG Mutations to Nonsense-Mediated mRNA Decay in Long QT Syndrome

, 2014
The degradation of human ether-a-go-go-related gene (hERG, KCNH2) transcripts containing premature termination codon (PTC)mutations by nonsense-mediatedmRNA decay (NMD) is an importantmechanismof long QT syndrome type 2 (LQT2).
Gong, Qiuming, Stump, Matthew R., Zhou, Zhengfeng   +2 more
core   +1 more source

Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) [PDF]

, 2019
This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Campofelice A., Di Leonardo A., Lentini L., Melfi R., Pace A., Pibiri I., Tutone M.   +6 more
core   +1 more source