Results 61 to 70 of about 80,402 (303)
Effects of PTCs on nonsense-mediated mRNA decay are dependent on PTC location
The récepteur d'origine nantais (RON) gene is a proto-oncogene that is responsible for encoding the human macrophage-stimulating protein (MSP) 1 receptor. MSP activation induces RON-mediated cell dissociation, migration and matrix invasion. Isoforms of RON that exclude exons 5 and 6 encode the RONΔ160 protein, which promotes cell transformation in ...
Heegyum, Moon +7 more
openaire +3 more sources
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin +7 more
wiley +1 more source
The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi +11 more
wiley +1 more source
Zhang S, Wang Q, Li D, et al. Cancer Manag Res. 2020;12:10389–10396. We, the Editors and Publisher of Cancer Management and Research, have retracted the following article.
Zhang S +9 more
doaj
Investigation into the strength, toughness and porosity of barium titanate PTC ceramics [PDF]
The effect of processing variables on the Strength and Toughness of n-doped Barium Titanate PTC Ceramics has been investigated. Fracture Toughness, K(_IC), has been measured using an indentation technique and a more conventional notched beam specimen ...
Blamey, Jonathan M.
core
T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li +11 more
wiley +1 more source
Vota PTC : La crisis tiene solución : Con una izquierda diferente
Tres homes ...
Partit del Treball de Catalunya (PTC)
core
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong +13 more
wiley +1 more source
Operational indicators of wheeled vehicles (WV), consumption of fuel and lubricants, urea, speed of cargo delivery, have always been and remain one of the key factors ensuring their high efficiency.
Vladimir S. Karabtsev, Danis Kh. Valeev
doaj +1 more source

