Results 131 to 140 of about 30,623 (153)

[The role and molecular mechanism of transcription factor EB and its target genes in multiple myeloma treatment with bortezomib]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhang RJ, Wang ZL, Shi XM, Zhang SY, Wang W, Ma MS, Li C, Gu CH, Zhang ZH.   +8 more
europepmc   +1 more source

FLNB and TTC26 regulate ciliary Hedgehog signaling to maintain intervertebral disc matrix homeostasis in adolescent idiopathic scoliosis. [PDF]

Genome Biol
Jiang H, Gao Y, Lai B, Wu J, Liao T, Zhang Z, Zhou X, Zhao J, Meng Y, Cai Z, Zhang C, Lai S, Gao R, Wang C, Li J, Yang F, Ding Y, Zhou X.   +17 more
europepmc   +1 more source

Integration-Associated Paraspinal Neoplasm after AAV Gene Therapy. [PDF]

N Engl J Med
Vo JN, Wu YM, Heider A, Cao X, Wang R, Pham T, Teo GC, Magge SN, Parmar H, Mody R, Robinson DR, Chinnaiyan AM.   +11 more
europepmc   +1 more source

Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability

Cancers, 2023
The Hedgehog receptor, Patched1 (PTCH1), is a well-known tumour suppressor. While the tumour suppressor’s activity is mostly ascribed to its function as a repressor of the canonical Smoothened/Gli pathway, its C-terminal domain (CTD) was reported ...
Gianluca Canettieri, Laura Di Magno, Natalia A. Riobo   +2 more
exaly   +2 more sources

New Mutations and an Updated Database for the Patched-1 (PTCH1) Gene

Molecular Genetics & Genomic Medicine, 2018
BackgroundBasal cell nevus syndrome (BCNS) is an autosomal dominant disorder characterized by multiple basal cell carcinomas (BCCs), maxillary keratocysts, and cerebral calcifications. BCNS most commonly is caused by a germline mutation in the patched-1 (
Marie G Reinders, Peter M Steijlen, Klara Mosterd   +2 more
exaly   +2 more sources

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PTCH1 Mutation Promotes Antitumor Immunity and the Response to Immune Checkpoint Inhibitors in Colorectal Cancer Patients

Cancer Immunology, Immunotherapy, 2022
Xiaotian Zhang, Xicheng Wang, Yanni Wang
exaly  

Differential Promoter Usages of PTCH1 and Down Regulation of HHIP Are Associated With HNSCC Progression

Pathology Research and Practice, 2022
Chinmay Kumar Panda, Neyaz Alam, Sankhadeep Dutta   +2 more
exaly