Results 1 to 10 of about 41,471 (240)
Nature Reviews Disease Primers, 2019 Under the term embryonal tumours, we examine the malignant neoplasms medulloblastomas, CNS-PNETs, AT/RTs, and ETANTRs. The common histological link between them is the small, round, blue cells which appear on H&E stains. They are considered highly malignant tumours (WHO Grade IV), although significant variation of prognosis exists between the ...
Paul A, Northcott +11 more
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Pediatric Hematology and Oncology, 1998 Medulloblastomas account for 20% of all primary brain tumors. The vast majority of them are sporadic. Familial medulloblastoma is very rare--only a few cases have been reported worldwide. Most were observed in siblings of the same sex. The affected children presented at various ages and all of them have died, usually within the first 2 years following ...
Moschovi, M +6 more
openaire +4 more sources
Adult desmoplastic medulloblastoma
Saudi Journal of Medicine and Medical Sciences, 2017 Medulloblastoma is more common in young age and rare in adult age. Some characteristics that characterize medulloblastoma in adults compared with children: Lateral cerebellar location, heterogeneous signal intensity on magnetic resonance imaging ...
Abdulrahman H Al Anazi +3 more
doaj +2 more sources
Paediatric desmoplastic medulloblastoma – Surgical treatment, adjuvant therapy, outcome survival (case series study) [PDF]
Romanian Journal of Neurology, 2020 Background. Desmoplastic medulloblastoma is a common adult cerebellar tumor. It has better than classic medulloblastoma outcome. This is a case series study followed up the cases of paediatric desmoplastic medulloblastoma and their treatment outcome and
Raad Ahmed Hussein +3 more
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RBM5-AS1 promotes radioresistance in medulloblastoma through stabilization of SIRT6 protein
Acta Neuropathologica Communications, 2021 Cancer stem cells (CSCs) contribute to radioresistance in medulloblastoma. Thus, identification of key regulators of medulloblastoma stemness is critical for improving radiotherapy for medulloblastoma.
Chuanying Zhu +3 more
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Analysis of risk factors of medulloblastoma recurrence based on the molecular subgroups
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Objective To investigate the recurrence rate and risk factors for the patients with medulloblastoma based on the molecular subgroups. Methods A retrospective study was conducted for the clinicopathological data of 67 medulloblastoma patients who were ...
LIU Hai⁃long +7 more
doaj +1 more source
PRMT1 is an important factor for medulloblastoma cell proliferation and survival
Biochemistry and Biophysics Reports, 2022 Aberrant expression of protein arginine methyltransferases (PRMTs) has been implicated in a number of brain tumors, but the role of PRMT1 in medulloblastoma, the most common malignant pediatric brain tumor, remains unexplored.
Xiao Gu +8 more
doaj +1 more source
iScience, 2023 Summary: We show that inactivating AMPK in a genetic medulloblastoma model depletes tumor stem cells and slows progression. In medulloblastoma, the most common malignant pediatric brain tumor, drug-resistant stem cells co-exist with transit-amplifying ...
Daniel Shiloh Malawsky +7 more
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Journal of Child Neurology, 2016 Medulloblastoma accounts for nearly 10% of all childhood brain tumors. These tumors occur exclusively in the posterior fossa and have the potential for leptomeningeal spread. Treatment includes a combination of surgery, radiation therapy (in patients >3 years old). Patients >3 years old are stratified based on the volume of postoperative residual
Nathan E, Millard, Kevin C, De Braganca
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Gene expression analyses of the spatio-temporal relationships of human medulloblastoma subgroups during early human neurogenesis. [PDF]
PLoS ONE, 2014 Medulloblastoma is the most common form of malignant paediatric brain tumour and is the leading cause of childhood cancer related mortality. The four molecular subgroups of medulloblastoma that have been identified - WNT, SHH, Group 3 and Group 4 - have ...
Cornelia M Hooper +4 more
doaj +1 more source