Results 11 to 20 of about 57,027 (223)

Modeling pediatric medulloblastoma [PDF]

open access: yesBrain Pathology, 2019
AbstractMouse models of medulloblastoma have proven to be instrumental in understanding disease mechanisms, particularly the role of epigenetic and molecular drivers, and establishing appropriate preclinical pipelines. To date, our research community has developed murine models for all four groups of medulloblastoma, each of which will be critical for ...
Roussel, Martine F.   +1 more
openaire   +3 more sources

Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency. [PDF]

open access: hybridNat Genet
Tao R   +45 more
europepmc   +3 more sources

Paediatric therapeutic development workshop on medulloblastoma. [PDF]

open access: yesBr J Cancer
\ua9 The Author(s) 2026. The second Paediatric Therapeutic Development Workshop focused on medulloblastoma. Between 60–70% of patients with medulloblastoma survive, but survivors have significant long-term side effects, and the highest-risk groups have a
Montiel Equihua C   +43 more
europepmc   +4 more sources

Molecular profiling of pediatric medulloblastoma in Kazakhstan: Genomic alterations, subgroup distribution, and survival. [PDF]

open access: yesBrain Pathol
A practical formalin‐fixed, paraffin‐embedded (FFPE)‐based molecular workflow integrating pathology, immunohistochemistry, and genomic profiling provides clinically meaningful subgroup classification of pediatric medulloblastoma and expands molecular evidence from an underrepresented Central Asian population. Abstract Medulloblastoma is the most common
Bolatov A   +9 more
europepmc   +2 more sources

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