Results 21 to 30 of about 33,884 (207)

Neurodegeneration-associated protein VAPB regulates proliferation in medulloblastoma

Scientific Reports, 2023
VAMP (Vesicle-associated membrane protein)-associated protein B and C (VAPB) has been widely studied in neurodegenerative diseases such as ALS, but little is known about its role in cancer.
Amanda Faria Assoni, Thiago Giove Mitsugi, René Wardenaar, Raiane Oliveira Ferreira, Elisa Helena Farias Jandrey, Gabriela Machado Novaes, Isabela Fonseca de Oliveira Granha, Petra Bakker, Carolini Kaid, Mayana Zatz, Floris Foijer, Oswaldo Keith Okamoto   +11 more
doaj   +1 more source

Metastatic Medulloblastoma [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1974
SUMMARY:The incidence of metastatic medulloblastoma is probably greater than the thirteen documented patients. Case reports of metastatic medulloblastoma must be carefully analysed. We have added two cases which conform to Weiss’ criteria for metastatic disease. The direction and factors influencing spread have been discussed.
D, Parkinson, R T, Ross, C B, Shields
openaire   +2 more sources

Low apparent diffusion coefficient in an extracranial brain tumor: a case report

Journal of Medical Case Reports, 2022
Background Medulloblastoma is well known as the most common malignant brain tumor identified in children, frequently found at an intra-axial location in the posterior cranial fossa. Extra-axial medulloblastoma is uncommon and often misdiagnosed.
Ho Xuan Tuan, Nguyen Duy Hung, Nguyen Dinh Minh, Nguyen Nhat Quang, Ngo Quang Duy, Nguyen Minh Duc   +5 more
doaj   +1 more source

LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells

Scientific Reports, 2021
Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor and an oncogene product, which plays a pivotal role in tumor progression.
Xiang Chen, Li Pan, Jia Wei, Ruijie Zhang, Xiaozhi Yang, Jinhua Song, Ren-Yuan Bai, Shengling Fu, Christopher R. Pierson, Jonathan L. Finlay, Chenglong Li, Jiayuh Lin   +11 more
doaj   +1 more source

Posterior fossa extra-axial variations of medulloblastoma: a pictorial review as a primer for radiologists

Insights into Imaging, 2021
Manifestations of an atypical variant of medulloblastoma of the posterior fossa in extra-axial locations have been reported, and key questions concerning its interpretation have been raised previously. This review illustrated the clinico-radiological and
Abdulaziz M. Al-Sharydah, Abdulrahman Hamad Al-Abdulwahhab, Sari Saleh Al-Suhibani, Wisam M. Al-Issawi, Faisal Al-Zahrani, Faisal Ahmad Katbi, Moath Abdullah Al-Thuneyyan, Tarek Jallul, Faisal Mishaal Alabbas   +8 more
doaj   +1 more source

Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells.

PLoS ONE, 2019
High morbidity and mortality are common traits of malignant tumours and identification of the cells responsible is a focus of on-going research. Many studies are now reporting the use of antibodies specific to Clusters of Differentiation (CD) cell ...
Jonathan P Robson, Marc Remke, Marcel Kool, Elaine Julian, Andrey Korshunov, Stefan M Pfister, Geoffrey W Osborne, Michael D Taylor, Brandon Wainwright, Brent A Reynolds   +9 more
doaj   +1 more source

Recent advances in SHH medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment [version 1; peer review: 2 approved]

F1000Research, 2019
Medulloblastoma, the most common of the malignant pediatric brain tumors, is a group of four molecularly and clinically distinct cancers with different cells of origin.
Lukas Tamayo-Orrego, Frédéric Charron
doaj   +1 more source

miR-196B-5P and miR-200B-3P Are Differentially Expressed in Medulloblastomas of Adults and Children

Diagnostics, 2020
Medulloblastoma is a highly aggressive brain tumor that typically affects children, while in adults it represents ~1% of all brain tumors. Little is known about microRNA expression profile of the rare adult medulloblastoma. The main aim of this study was
Michela Visani, Gianluca Marucci, Dario de Biase, Felice Giangaspero, Francesca Romana Buttarelli, Alba Ariela Brandes, Enrico Franceschi, Giorgia Acquaviva, Alessia Ciarrocchi, Kerry Jane Rhoden, Giovanni Tallini, Annalisa Pession   +11 more
doaj   +1 more source

Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups. [PDF]

PLoS ONE, 2017
Medulloblastoma comprises four main subgroups (WNT, SHH, Group 3 and Group 4) originally defined by transcriptional profiling. In primary medulloblastoma tissues, these groups are thought to be distinguishable using the immunohistochemical detection of β-
Petr Chlapek, Karel Zitterbart, Leos Kren, Lenka Filipova, Jaroslav Sterba, Renata Veselska   +5 more
doaj   +1 more source

MRI features as a helpful tool to predict the molecular subgroups of medulloblastoma: state of the art

Therapeutic Advances in Neurological Disorders, 2018
Medulloblastoma is the most common malignant pediatric brain tumor. Medulloblastoma should not be viewed as a single disease, but as a heterogeneous mixture of various subgroups with distinct characteristics.
Giovanna Stefania Colafati, Ioan Paul Voicu, Chiara Carducci, Evelina Miele, Andrea Carai, Simona Di Loreto, Antonio Marrazzo, Antonella Cacchione, Valerio Cecinati, Assunta Tornesello, Angela Mastronuzzi   +10 more
doaj   +1 more source