Results 21 to 30 of about 57,027 (223)

Biomaterial-Enabled Delivery Strategies to Overcome Treatment Resistance in Medulloblastoma. [PDF]

Int J Nanomedicine
Sheng Z, Dong Y, Wei J, Li J, Min L, Chen Y, Wang B, Wen Y, Song YX, Wang J, Gao J, Wang X.   +11 more
europepmc   +3 more sources

Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial [PDF]

, 2015
Purpose: To improve stratification of risk-adapted treatment for non-metastatic (M0), standard-risk medulloblastoma patients by prospective evaluation of biomarkers of reported biological or prognostic significance, alongside clinico-pathological ...
Schwalbe, Ed, Schwalbe, Ed C, Hicks, Debbie, Figarella-Branger, Dominique, Lannering, Birgitta, Clifford, Steven, Nicholson, Sarah, Toole, Kieran O', Lannering, Birgitta,, Clifford, Steven C, zur Mühlen, Anja, Rutkowski, Stefan, O'Toole, Kieran, Goschzik, Tobias, Doz, François, Nicholson, Sarah Leigh, Gustafsson, Göran, Pietsch, Torsten, Lannering, B, Hicks, D, O'Toole, K, Nicholson, SL, zur, Muehlen A, Goschzik, T, Doz, F, Clifford, SC, Figarella-Branger, D, Schwalbe, EC   +27 more
core   +1 more source

Local delivery of interferon restores antigen presentation and sensitizes medulloblastoma to T cell killing. [PDF]

Proc Natl Acad Sci U S A
Eisemann T, Chambers KR, Beigi Masihi M, Tzaridis T, Gc S, Pister V, Youm I, Dutta A, Wenzel AT, Chin K, Xu Z, Pei Y, Pomeroy SL, Mesirov JP, Fraenkel E, Bagchi A, Chavez L, Wechsler-Reya RJ.   +17 more
europepmc   +3 more sources

Medulloblastoma tumor suppressor factor RENKCTD11: structure and function based design and development of new compounds of theraupetical interest. [PDF]

, 2009
Hedgehog (Hh) signaling is suggested to be a major oncogenic pathway in medulloblastoma, which arises from aberrant development of cerebellar granule progenitors.
Pirone, Luciano
core   +1 more source

Spatial and single-cell dissection of medulloblastoma identifies developmental hierarchies and a prognostic PPIA-BSG tumor-immune axis. [PDF]

J Transl Med
Chen M, Duan B, Zhang J, Daniels C, Hu C, Yuan J, Guo J, Taylor MD, Shi X, Zhang L, Li D, Sun T.   +11 more
europepmc   +2 more sources

Identification and validation of feature genes using a ferroptosis-informed analytical framework in medulloblastoma [PDF]

Front Pediatr
Chen X, Li S, Yang K, Liu Y, Zhan Q.
europepmc   +3 more sources

Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype. [PDF]

, 2016
The childhood brain tumor, medulloblastoma, includes four subtypes with very different prognoses. Here, we show that paracrine signals driven by mutant β-catenin in WNT-medulloblastoma, an essentially curable form of the disease, induce an aberrant ...
Wadhwa, Elizabeth, Cho, Yoon-Jae, Patel, Yogesh, Gilbertson, Richard, Finkelstein, David, Perreault, Sebastien, Patmore, Deanna, Jacus, Megan, Phoenix, Timothy, Roussel, Martine, Boulos, Nidal, Boop, Scott, Stewart, Clinton, Goumnerova, Liliana   +13 more
core   +3 more sources

Adult medulloblastoma [PDF]

, 2016
Medulloblastoma is a highly malignant central nervous system (CNS) tumor that arises from the cerebellum. It is the most common primary malignant intracranial childhood neoplasm.
Rege, S. V., Narayan, Sharadendu, Patil, Harshad   +2 more
core   +1 more source

Genome-wide analysis of gene expression and alternative splicing in human medulloblastoma [PDF]

, 2010
Medulloblastoma is a malignant embryonal tumour of the cerebellum which most commonly affects children. A subset of tumours is thought to arise from cerebellar granule cell precursors (GCPs) that fail to undergo normal neuronal development, following ...
Menghi, F.
core  

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source