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A Prebiotic Synthesis of Pterins

Chemistry – A European Journal, 2015
AbstractThe genesis of life on Earth is a hypothesis of evolutionary science that can be, at least partially, tested experimentally. The prebiotic synthesis of cofactors or coenzymes is a poorly explored issue, likely because their formation under plausible prebiotic conditions is not clear.
Margarita R, Marín-Yaseli   +2 more
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Inborn Errors of Pterin Metabolism

Annual Review of Nutrition, 1988
HY PERPHENY LALANINEMIA DUE TO TETRAHYDROBIOPTERIN DEFICIENCy 188 GTP Cyclohydrolase I Deficiency 188 6-Pyruvoyl Tetrahydropterin Synthase Deficiency 189 Dihydropteridine Reductase Deficiency 191 Other Forms ...
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Nitric-Oxide-Synthase Inhibitors II — Pterin Antagonists/Anti-Pterins

2000
In addition to heme, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), nitric oxide synthases (NOS) require tetrahydrobiopterin (H4B). This was first demonstrated for homogenates of stimulated murine macrophages (KWON et al. 1989; TAYEH and MARLETTA 1989). Unlike other enzymes, e.g.
E. R. Werner, H. H. H. W. Schmidt
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Synthese einiger Pterine

Helvetica Chimica Acta, 1948
AbstractDie Herstellung folgender Pterine wird beschrieben: 2‐Äthyl‐thio‐6‐oxypteridin, 2‐Äthylthio‐6‐oxy‐8,9‐diphenylpteridin, 2‐Äthyl‐thio‐6‐oxy‐8,9‐dimethylpteridin, 2‐Äthylthio‐6‐oxy‐8,9‐phenanthreno‐pteridin, 2‐Äthylthio‐6‐oxy‐8,9‐acenaphtenopteridin, 6‐Amino‐iso‐xanthopterin‐carbonsäure, Desimino‐isoxanthopterincarbonsäure.
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�ber Pterine bei Algen

Archiv f�r Mikrobiologie, 1962
In elf verschiedenen Gattungen aus sechs Klassen der Algen wurde neben den Streptococcus faecalis-aktiven Verbindungen der Folsaure-Gruppe im Wachstumstest mit Crithidia fasciculata “unkonjugiertes” Pterin nachgewiesen. Dieses besitzt — als Voraussetzung fur seine Wirksamkeit gegenuber Crithidia — an Stelle der p-Aminobenzoylglutaminsaure eine ...
I. Ziegler, H. Ziegler, H. Schmidt
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Inhibition of xanthine oxidase by pterins

Free Radical Research, 1998
The effect of a panel of pterins on xanthine oxidase was investigated by measuring formation of urate from xanthine as well as formazan production from nitroblue tetrazolium. The pterin derivatives, depending on their chemical structure, decreased urate as well as formazan generation: 200 microM neopterin and biopterin suppressed urate formation (90 ...
I, Wede   +4 more
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Pyrimidine, Purine, Pterine

1958
Die in diesem Kapitel zusammengefassten Verbindungen zeichnen sich durch einen relativ hohen Stickstoffgehalt aus.
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Urinary Pterins in Lesch-Nyhan Syndrome

1991
The Lesch-Nyhan syndrome results from a complete deficiency of the purine salvage enzyme hypoxanthine guanine phosphoribosyltransferase (HPRT E.C.2.4.2.8). Clinical manifestations include muscle hypotonia, torsion dystonia, delayed motor development, compulsive self-mutilative behaviour, and mental handicap, as well as increased quantities of uric acid
I, Sebesta   +3 more
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