Vanadium Compounds as PTP Inhibitors [PDF]
Molecules, 2017 Phosphotyrosine signaling is regulated by the opposing actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). Here we discuss the potential of vanadium derivatives as PTP enzyme inhibitors and metallotherapeutics. We describe how vanadate in the V oxidized state is thought to inhibit PTPs, thus acting as a pan-inhibitor of
Andrew Stoker
exaly +5 more sources
Entertainment Sedentary Time and Subjective Well-Being in College Students: A Moderation Model of Perceived Time Poverty [PDF]
Behavioral SciencesThis study examined the association between entertainment sedentary time (EST) and subjective well-being (SWB) among Chinese college students and further explored the moderating role of perceived time poverty (PTP).
Lin-Ming Li +9 more
doaj +2 more sources
The physiochemical characteristics of Phragmites communis trin polysaccharides and in vitro anti-diabetic effects of their different fractions [PDF]
Frontiers in PharmacologyThis study isolated and purified two polysaccharide fractions, PTP-1 and PTP-2, from Phragmites communis Trin root via cellulase-assisted ultrasonication and DEAE chromatography, with purities of 90.56% and 91.35%, respectively.
Wei Gao +18 more
doaj +2 more sources
Targeting LMW‐PTP to sensitize melanoma cancer cells toward chemo‐ and radiotherapy
Cancer Medicine, 2018 Tumor resistance to apoptosis is one the main causes of anticancer treatment failure. Previous studies showed that LMW‐PTP overexpression enhances resistance of cancer cells to traditional anticancer drugs.
Paolo Paoli +2 more
exaly +2 more sources
Performance study of a coexistence system in a PON network taking into account the stimulated scattering of Raman [PDF]
E3S Web of Conferences, 2022 Some problems introduced by the need for coexistence between a Passive Optical Network PON technologies (GPON, XGS-PON, and NG-PON2 in particular) especially the Stimulated Raman Scattering SRS which appears when different PON technologies transfer ...
Kherici Cheikh, Kandouci Malika
doaj +1 more source
Вавиловский журнал генетики и селекции, 2022 In this article, the system of the green microalgal genus Micractinium, based on morphological, physiological, ecological and molecular data, is considered.
E. S. Krivina +2 more
doaj +1 more source
Foods, 2022 Obesity and overweight have serious health outcomes. “Phikud Tri-Phon” (PTP) is a traditional Thai medicine comprising three dried fruits from Aegle marmelos L., Morinda citrifolia L., and Coriandrum sativum L.
Ngamrayu Ngamdokmai +6 more
doaj +1 more source
Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death. [PDF]
PLoS ONE, 2010 Prolonged opening of the mitochondrial permeability transition pore (PTP) leads to cell death. Various ubiquinone analogs have been shown to regulate PTP opening but the outcome of PTP regulation by ubiquinone analogs on cell fate has not been studied ...
Flavien Devun +5 more
doaj +1 more source
HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain. [PDF]
PLoS ONE, 2009 The HD-PTP protein has been described as a tumor suppressor candidate and based on its amino acid sequence, categorized as a classical non-transmembrane protein tyrosine phosphatase (PTP).
Marie-Claude Gingras +6 more
doaj +1 more source
Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse. [PDF]
PLoS ONE, 2010 T cell protein tyrosine phosphatase (TC-PTP/PTPN2) is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation.
Syed-Wajahat Hassan +5 more
doaj +1 more source