Results 111 to 120 of about 111,177 (248)

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

Plant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang, Anqin Gao, Tsz‐Yan Chan, Hafiz Mamoon Rehman, Sehar Nawaz, Sehrish Bashir, Noman Mahmood, Muhammad Wajid Ullah, Chunlin Long, Hon‐Ming Lam, Muhammad Arif   +10 more
wiley   +1 more source

Molecular characterization of CD36 deficiency in blood donors of Middle Eastern and African origin reveals transcript‐level defects beyond genomic variants

Transfusion, EarlyView.
Abstract Background The increasing diversity of blood donor populations has created new challenges for transfusion services worldwide. The identification of donors lacking relevant high‐prevalence antigens is becoming increasingly important to ensure compatible blood products for alloimmunized patients and to support the development of rare donor ...
Sarah Petermann, Inga Stellmacher, Brigitte K. Flesch, Tanja Rehling, Irina Häcker, Marc F. Schetelig, Alexander Carbol, Lambros Kordelas   +7 more
wiley   +1 more source

Untersuchungen zur Regulierung und Funktion der Mitogen-aktivierten Proteinkinase ERK5 = Regulation and Function of the Mitogen-activated Protein Kinase ERK5 [PDF]

, 2003
Mitogen activated protein kinases (MAPKs) are found in all eukaryotic cells and represent crucial elements in the signal transduction from the plasma membrane to the nucleus.
Buschbeck, Marcus
core  

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

The Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin, Andrea Carrer, Federica Boscolo Nata, Elena Frigo, Federico Fogolari, Giovanna Lippe, Michela Carraro, Paolo Bernardi   +7 more
wiley   +1 more source

Sustainable and Seismically Resilient Confined Masonry: Global Progress in Research and Design Practice

Earthquake Spectra, Volume 42, Issue 4, November 2026.
Modern confined masonry (CM) construction consists of masonry walls confined by reinforced concrete (RC) tie‐columns and tie‐beams. When built correctly, CM buildings have shown good performance in earthquake's shaking. Even though CM construction has been practised for almost a century in some Latin American countries, its use and standardisation are ...
Ahsana Parammal Vatteri, Svetlana Brzev, Dina D’Ayala, Sergio M. Alcocer, Sebastian Kaminski, Vaibhav Singhal, Aidarbek Stamov, Anna Pavan, Daniel Quiun, Dexter Lo, Erwin Lim, Hemant B. Kaushik, Juan José Pérez‐Gavilán, Julian Thamboo, Mahdi Eghbali, Marcos M. Chávez, Qaisar Ali, Ramesh Guragain, Sofia Andrade, Tim Hart, Ulugbek Begaliev, Yunita Idris, Radu Vacareanu, Daniar Abdykalykov   +23 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, Volume 600, Issue 17, Page 2579-2614, September 2026.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov‐Excited Luminescence Imaging (CELI) of Oxygen

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Biocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Simin Belali, Marien Iliza Ochoa Mendoza, Matthew S. Reed, Danylo Mykhalchuk, Annemarie Lang, Joel D. Boerckel, Brian W. Pogue, Sergei A. Vinogradov   +7 more
wiley   +1 more source

Role of PTP in beta cell apoptosis

, 2012
Implication du PTP dans la mort cellulaire β pancréatique L'hyperglycémie, l'hyperfructosémie et l'ischémie-reperfusion sont délétères pour la viabilité cellulaire β pancréatique, jouant un rôle majeur dans la perte de la masse cellulaire β.
Cornali Lablanche, Sandrine
core  

Lack of Inhibitor Development in Previously Treated People With Haemophilia Switching Factor Products—Final Results of Athn 2: Factor Switching Study

Haemophilia, EarlyView.
Erin Cockrell, Martin Chandler, Tammuella Chrisentery‐Singleton, Stacy E. Croteau, Nabil Daoud, Michael F. Guerrera, M. Nikki Hirsh, Janna Journeycake, Roshni Kulkarni, Susan U. Lattimore, Catherine McGuinn, Margaret Ragni, Michael Recht, Ulrike M. Reiss, Robert Sidonio Jr., Cliffford M. Takemoto, Michael Tarantino, Annette von Drygalski, Ellis J. Neufeld   +18 more
wiley   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, Volume 13, Issue 52, 18 September 2026.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source