Results 121 to 130 of about 112,141 (241)

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, Volume 159, Issue 11, Page 2633-2652, 1 December 2026.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Self‐Assembly of Therapeutic Peptides for Enhanced Cancer Therapy: Strategies, Therapeutic Performance, and Future Perspectives

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Therapeutic peptide self‐assembly is governed by multiple non‐covalent interactions, enabling the construction of diverse supramolecular structures. These self‐assembled systems can be engineered through spontaneous self‐assembly of monomers, co‐assembly, or stimulus‐responsive strategies to improve tumor delivery efficiency.
Yuelin Fang, Xue Wan, Shihe Wang, Honglan Dai, Huiling Zeng, Nan Chen, Xinxin Zhang   +6 more
wiley   +1 more source

Effects of Different pH Levels on the Structural and Functional Properties of Proteins of Phaeodactylum tricornutum

Molecules
Phaeodactylum tricornutum is identified by its capacity for rapid growth, reproduction, and in vitro cultivation, as well as the presence of a range of high-value active compounds, including proteins, with potential food applications.
Yanli Wang, Laijing Zhu, Zhunyao Zhu, Meng Liu, Xiangzhong Zhao   +4 more
doaj   +1 more source

Colocalisation of the protein tyrosine phosphatases PTP-SL and PTPBR7 with beta4-adaptin in neuronal cells.

, 2003
The mouse gene Ptprr encodes the neuronal protein tyrosine phosphatases PTP-SL and PTPBR7. These proteins differ in their N-terminal domains, with PTP-SL being a cytosolic, membrane-associated phosphatase and PTPBR7 a type I transmembrane protein.
Schepens, J.T.G., Pepers, B.A., Dilaver, G., Maagdenberg, A.M.J.M. van den, Fransen, J.A.M., Hendriks, W.J.A.J., Wijers-Rouw, M.J.P.   +6 more
core   +1 more source

Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025)

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang, Jinqin Wei, Zhao Jiang, Yingming Luo, Yan Zhou, Jiafan Yang, Hui Cui   +6 more
wiley   +1 more source

基于PTP协议的多跳无线回程网络时间同步误差补偿方法

, 2017
The present invention relates to a wireless network communication technology, and in particular to a time synchronization error compensation method for multi-hop wireless backhaul network based on PTP.
Wang ZW(王照伟), Li ZB(李志博), Li D(李栋), Wang JT(王金涛), Zeng P(曾鹏)   +4 more
core  

Sustainable and Seismically Resilient Confined Masonry: Global Progress in Research and Design Practice

Earthquake Spectra, Volume 42, Issue 4, November 2026.
Modern confined masonry (CM) construction consists of masonry walls confined by reinforced concrete (RC) tie‐columns and tie‐beams. When built correctly, CM buildings have shown good performance in earthquake's shaking. Even though CM construction has been practised for almost a century in some Latin American countries, its use and standardisation are ...
Ahsana Parammal Vatteri, Svetlana Brzev, Dina D’Ayala, Sergio M. Alcocer, Sebastian Kaminski, Vaibhav Singhal, Aidarbek Stamov, Anna Pavan, Daniel Quiun, Dexter Lo, Erwin Lim, Hemant B. Kaushik, Juan José Pérez‐Gavilán, Julian Thamboo, Mahdi Eghbali, Marcos M. Chávez, Qaisar Ali, Ramesh Guragain, Sofia Andrade, Tim Hart, Ulugbek Begaliev, Yunita Idris, Radu Vacareanu, Daniar Abdykalykov   +23 more
wiley   +1 more source

Untersuchung der biologischen Funktion der Proteintyrosinphosphatase PTP-BL

, 2003
Die PTP-BL besteht aus einer N-terminalen FERM-Domäne, 5 PDZ-Domänen und einer C-terminalen PTP-Domäne. Hier wird gezeigt, daß PTP-BL an der Regulation der Cytokinese beteiligt ist. Die für das vollständige Protein kodierende cDNA wurde amplifiziert und
Herrmann, Lutz (Dipl.)
core   +1 more source

Inhibition of VE-PTP rejuvenates Schlemm's canal in aged mice and acts via Tie2.

PLoS ONE
PurposeGlaucoma is the leading cause of irreversible blindness worldwide and is associated with high intraocular pressure (IOP). Schlemm's canal (SC), a hybrid vessel present in the anterior part of the eye, is known to control IOP by draining aqueous ...
Sarthak Mishra, Ute Ipe, Astrid F Nottebaum, Kevin G Peters, Dietmar Vestweber   +4 more
doaj   +1 more source

Beyond Bioenergetics: Moonlighting Functions of F1FO‐ATPase From ATP Synthesis to an ATP‐Wasting Death Switch

Medicinal Research Reviews, Volume 46, Issue 6, Page 2013-2016, November 2026.
ABSTRACT Mitochondrial F1FO‐ATPase is classically viewed as the “splendid” rotary nanomachine that sustains life by converting the proton‐motive force (pmf) into ATP. Yet this same complex can adopt a second, context‐dependent function that links bioenergetics to cell fate.
Salvatore Nesci
wiley   +1 more source