Results 1 to 10 of about 329,921 (388)

Clinician-administered PTSD scale: A review of the first ten years of research

Depression and Anxiety, 2001
The Clinician‐Administered PTSD Scale (CAPS) is a structured interview for assessing posttraumatic stress disorder (PTSD) diagnostic status and symptom severity.
Frank W. Weathers, Terence M. Keane, Jonathan Davidson   +2 more
openalex   +2 more sources

Severe PTSD or just PTSD? [PDF]

European Journal of Psychotraumatology
Although the widespread of trauma exposure, post-traumatic stress disorder (PTSD) remains a prevalent and disabling mental disorder. Yet, access to appropriate care, particularly for individuals with more severe forms, remains limited.
Valentin Raymond, Antoine Yrondi, Philippe Birmes   +2 more
doaj   +2 more sources

MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial

Nature Network Boston, 2023
This multi-site, randomized, double-blind, confirmatory phase 3 study evaluated the efficacy and safety of 3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) versus placebo with identical therapy in participants with moderate to severe post ...
Jennifer M. Mitchell, M. Ot’alora G., Bessel A van der Kolk, Scott Shannon, Michael P Bogenschutz, Yevgeniy Gelfand, Casey Paleos, Christopher R. Nicholas, Sylvestre Quevedo, Brooke Balliett, S. Hamilton, M. Mithoefer, Sarah Kleiman, K. Parker-Guilbert, Keren Tzarfaty, Charlotte Harrison, A. de Boer, R. Doblin, B. Yazar-Klosinski   +18 more
semanticscholar   +1 more source

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study

Nature Network Boston, 2021
Post-traumatic stress disorder (PTSD) presents a major public health problem for which currently available treatments are modestly effective. We report the findings of a randomized, double-blind, placebo-controlled, multi-site phase 3 clinical trial ...
Jennifer M. Mitchell, M. Bogenschutz, Alia Lilienstein, C. Harrison, Sarah E. Kleiman, K. Parker-Guilbert, M. Ot’alora G., W. Garas, Casey Paleos, I. Gorman, Christopher R. Nicholas, M. Mithoefer, Shannon Carlin, Bruce Poulter, A. Mithoefer, Sylvestre Quevedo, G. Wells, Sukhpreet Klaire, B. A. van der Kolk, Keren Tzarfaty, R. Amiaz, Ray Worthy, Scott M. Shannon, J. Woolley, C. Marta, Y. Gelfand, Emma Hapke, Simon Amar, Yair Wallach, Randall W. Brown, S. Hamilton, Julie B. Wang, A. Coker, Rebecca Matthews, A. de Boer, B. Yazar-Klosinski, A. Emerson, R. Doblin   +37 more
semanticscholar   +1 more source

Neural valuation of rewards and punishments in posttraumatic stress disorder: a computational approach

Translational Psychiatry, 2023
Posttraumatic stress disorder (PTSD) is associated with changes in fear learning and decision-making, suggesting involvement of the brain’s valuation system.
Ruonan Jia, Lital Ruderman, Robert H. Pietrzak, Charles Gordon, Daniel Ehrlich, Mark Horvath, Serena Mirchandani, Clara DeFontes, Steven Southwick, John H. Krystal, Ilan Harpaz-Rotem, Ifat Levy   +11 more
doaj   +1 more source

Centrally acting anticholinergic drug trihexyphenidyl is highly effective in reducing nightmares associated with post‐traumatic stress disorder

Brain and Behavior, 2021
Introduction Following a case study on scopolamine butyl bromide, an anticholinergic drug, we studied the effect of a central anticholinergic drug on post‐traumatic stress disorder (PTSD)‐related flashbacks and nightmares.
Katsumasa Sogo, Masanobu Sogo, Yoshie Okawa   +2 more
doaj   +1 more source

For whom the bell tolls: psychopathological and neurobiological correlates of a DNA methylation index of time-to-death

Translational Psychiatry, 2022
Psychopathology is a risk factor for accelerated biological aging and early mortality. We examined associations between broad underlying dimensions of psychopathology (reflecting internalizing and externalizing psychiatric symptoms), PTSD, and age ...
Sage E. Hawn, Xiang Zhao, Danielle R. Sullivan, Mark Logue, Dana Fein-Schaffer, William Milberg, Regina McGlinchey, Mark W. Miller, Erika J. Wolf   +8 more
doaj   +1 more source

A Glimpse into the “Black Box”: Which Elements of Consultation in an EBP are Associated with Client Symptom Change and Therapist Fidelity?

Implementation Research and Practice, 2021
Background: Consultation is an implementation strategy that improves delivery and clinical outcomes for Cognitive Processing Therapy (CPT), an evidence-based practice (EBP) for posttraumatic stress disorder (PTSD).
Kera Mallard Swanson, Jiyoung Song, Matthew Beristianos, Syed Aajmain, Jeanine E.M. Lane, Meredith S.H. Landy, Michael K. Suvak, Norman Shields, Candice M. Monson, Shannon Wiltsey Stirman   +9 more
doaj   +1 more source

COVID-19 Pandemic in the Italian Population: Validation of a Post-Traumatic Stress Disorder Questionnaire and Prevalence of PTSD Symptomatology

International Journal of Environmental Research and Public Health, 2020
Since December 2019, the COVID-19 pandemic has attracted worldwide attention for its rapid and exponential diffusion. The long-term psychological impact, of both the spread of the virus and the restrictive policies adopted to counteract it, remains ...
G. Forte, F. Favieri, R. Tambelli, M. Casagrande   +3 more
semanticscholar   +1 more source

Screening for PTSD and TBI in Veterans using Routine Clinical Laboratory Blood Tests

Translational Psychiatry, 2023
Post-traumatic stress disorder (PTSD) is a mental disorder diagnosed by clinical interviews, self-report measures and neuropsychological testing. Traumatic brain injury (TBI) can have neuropsychiatric symptoms similar to PTSD.
Mu Xu, Ziqiang Lin, Carole E. Siegel, Eugene M. Laska, Duna Abu-Amara, Afia Genfi, Jennifer Newman, Michelle K. Jeffers, Esther M. Blessing, Steven R. Flanagan, Silvia Fossati, Amit Etkin, Charles R. Marmar   +12 more
doaj   +1 more source