Results 41 to 50 of about 165,528 (301)

Update to an evaluation of ICD-11 PTSD and complex PTSD criteria in a sample of adult survivors of childhood institutional abuse by Knefel & Lueger-Schuster (2013): a latent profile analysis [PDF]

European Journal of Psychotraumatology, 2015
Background: The World Health Organization (WHO) International Classification of Diseases, 11th version (ICD-11), has proposed a trauma-related diagnosis of complex posttraumatic stress disorder (CPTSD) separate and distinct from posttraumatic stress ...
Matthias Knefel, Donn W. Garvert, Marylene Cloitre, Brigitte Lueger-Schuster   +3 more
doaj   +1 more source

PTSD – an update for general practitioners [PDF]

, 2014
Provides up-to-date guidance for general practitioners (GPs) in the recognition of PTSD and the current best practice recommendations for pharmacological and psychological treatment. Background Australians are commonly exposed to traumatic events, which
John Cooper, Andrea Phelps, Olivia Metcalf   +2 more
core  

Effect Modification of Cigarette Smoking on the Relationship Between Posttraumatic Stress Disorder, Other Mental Health Conditions, and Rheumatoid Arthritis Risk: A Large Case‐Control Study in US Veterans

Arthritis Care &Research, EarlyView.
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr, Harlan Sayles, Tate M. Johnson, Joshua F. Baker, Punyasha Roul, Grant W. Cannon, Gary A. Kunkel, Katherine D. Wysham, Gail S. Kerr, Amir A. Razmjou, Isaac Smith, Jennifer L. Barton, Maria I. Danila, Jonathan S. Richards, Bryant R. England, Ted R. Mikuls   +15 more
wiley   +1 more source

Circulating biomarkers and neuroanatomical brain structures differ in older adults with and without post-traumatic stress disorder

Scientific Reports
The aim of this study was to advance post-traumatic stress disorder (PTSD) understanding in older adults (48–77 years) by determining if circulating cytokines (IL-1β, IL-2, IL-4, IL-6, IL-12p70, IL17A and TNFα), brain-derived neurotrophic factor (BDNF ...
Bonnie L. Quigley, Nathan Wellington, Jacob M. Levenstein, Megan Dutton, Ana P. Bouças, Grace Forsyth, Cyrana C. Gallay, Maryam Hajishafiee, Ciara Treacy, Jim Lagopoulos, Sophie C. Andrews, Adem T. Can, Daniel F. Hermens   +12 more
doaj   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

Clinical Epigenetics
Background Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the influences of
Mark W. Miller, Erika J. Wolf, Xiang Zhao, Mark W. Logue, Sage E. Hawn   +4 more
doaj   +1 more source

The Role of Social Support as A Moderator in the Relationship between Resilience and PTSD in Individuals Who are COVID-19 Survivors Who Have Comorbidities

Guidena, 2023
The COVID-19 pandemic has an impact on individual health conditions, especially COVID-19 survivors who have comorbidities. Therefore, to reduce PTSD experienced by COVID-19 survivors, resilience and social support are needed. This study aims to determine
Farras Aisha Dzahabiya, Roswiyani Roswiyani, Riana Sahrani   +2 more
doaj   +1 more source

Propofol Modulates Fear Memory Reconsolidation by Inhibiting D2 Receptor‐Expressing Neurons in the Medial Prefrontal Cortex

Advanced Science, EarlyView.
This study shows that propofol modulates fear‐memory reconsolidation in mice. It works by suppressing D2 receptor‐expressing neurons within the medial prefrontal cortex and their connections to the basolateral amygdala. D2‐receptor agonists reproduce this fear‐reducing effect, offering potential non‐anesthetic therapeutic strategies for trauma‐related ...
Jie Li, Yi‐Ge Guo, Xing Xu, Gui‐Lin Meng, Han Li, Liu‐Wei Chu, Xin‐Yuan Chen, Xiao‐Yun Guo, Tao Xu, Ti‐Fei Yuan, Ji Hu, Xiao‐Na Zhu   +11 more
wiley   +1 more source

CUE: CpG impUtation ensemble for DNA methylation levels across the human methylation450 (HM450) and EPIC (HM850) BeadChip platforms

Epigenetics, 2021
DNA methylation at CpG dinucleotides is one of the most extensively studied epigenetic marks. With technological advancements, geneticists can profile DNA methylation with multiple reliable approaches.
Gang Li, Laura Raffield, Mark Logue, Mark W. Miller, Hudson P. Santos, T. Michael O’Shea, Rebecca C. Fry, Yun Li   +7 more
doaj   +1 more source

Role and treatment of early maladaptive schemas in Vietnam veterans with PTSD [PDF]

, 2009
The first study examined the role of perceived adverse parenting and early maladaptive schemas in the development of PTSD in Australian and New Zealand Vietnam war-veterans (N = 220).
Cockram, David McEwan
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