Results 141 to 150 of about 16,818 (287)

Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross‐sectional comparative echocardiographic study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari, Melis Pehlivantürk Kizilkan, Musa Öztürk, İlker Ertuğrul, Hayrettin Hakan Aykan, Tevfik Karagöz, Nuray Kanbur, Orhan Derman, Sinem Akgül   +8 more
wiley   +1 more source

Association between parental age at childbirth and timing of puberty in children: an 8-year cohort study

Biology of Sex Differences
Background The timing of puberty in offspring is influenced by various factors, including genetics and environment. While some studies suggest a link between parental age at childbirth and pubertal timing, the evidence remains inconsistent.
Qin Zhang, Chengpeng Cui, Zeqin Peng, Siyan Ye, Yan Li, Di Wu, Qin Liu   +6 more
doaj   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

Interdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu, Lulu Li, Ying Cao, Ying Wang, Chao Yang, Alexander Nikolaevich Orekhov, Yuanfeng Lu, Houbin Chu, Chuanrong Zhao, Guixue Wang, Guohua Song   +10 more
wiley   +1 more source

Timing of menarche and pubertal growth patterns using the QEPS growth model

Frontiers in Pediatrics
ObjectivesTo explore the timing of menarche, postmenarcheal growth, and to investigate the impact of various variables on menarcheal age and postmenarcheal and pubertal growth.Study DesignThis longitudinal community population-based study analyzed ...
Jenni Gårdstedt-Berghog, Jenni Gårdstedt-Berghog, Aimon Niklasson, Agneta Sjöberg, A. Stefan Aronson, A. Stefan Aronson, Aldina Pivodic, Aldina Pivodic, Andreas F. M. Nierop, Andreas F. M. Nierop, Kerstin Albertsson-Wikland, Anton Holmgren, Anton Holmgren, Anton Holmgren   +13 more
doaj   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Profiles of Digital Parenting Styles: Associations With Cyberbullying Among Adolescents

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Cyberbullying is a growing concern in the digital age, posing serious threats to children's mental health, social relationships, and overall well‐being. Parents raising children in a highly digitalized world employ a range of digital parenting strategies, including active monitoring, content regulation, and technology control, to ...
Yeseul Lee, Jennifer L. Doty, Xiaoqi Ma, Tracy Evian Waasdorp   +3 more
wiley   +1 more source

Childhood Body Mass Index and Pubertal Timing - Changes over time and associations with adult cardiovascular mortality

, 2019
Puberty in boys has long been an under-investigated area of research mainly due to the lack of an easily available pubertal marker, corresponding to menarche for girls.
Bygdell, Maria
core  

Examining Causal Determinants of Childhood Obesity and Pubertal Timing

Childhood obesity is a rapidly escalating public health crisis, with prevalence rates increasing from 4% in 1975 to 18% in 2016 among children aged 5-19 years worldwide.

core   +1 more source

A Latent Profile Analysis of Body Image and Disordered Eating Attitudes and Behaviors in Adolescent Boys

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Adolescence is a risk period for body dissatisfaction which can contribute to eating disorder development. Given sex or gender differences in body image and disordered eating, it is critical to examine body image and eating concerns in adolescent boys and whether mindfulness is associated with body image and eating attitudes and ...
Madeline R. Olwert, Shelley R. Hart, Delwin Carter, Natalie R. Stromberg   +3 more
wiley   +1 more source