Results 251 to 260 of about 2,220,873 (330)

Clinical Features of Malignant Ovarian Germ Cell Tumors According to Demographic and Pathologic Characteristics

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Malignant ovarian germ cell tumors (MOGCTs) are aggressive cancers affecting mainly young women, in whom fertility preservation is important. Diagnosis is often delayed because early symptoms are non‐specific, leading to advanced disease or emergency surgery that may limit optimal staging and fertility‐sparing treatment. As
Jila Agah, Elham Navipour, Setareh Akhavan, Somaye Norouzi   +3 more
wiley   +1 more source

Puberty-Promoting Treatment and Psychosocial Well-Being in Boys With Constitutional Delay of Puberty: A Randomized Controlled Trial. [PDF]

Clin Endocrinol (Oxf)
Kariola L, Varimo T, Lääperi M, Huopio H, Tenhola S, Voutilainen R, Toppari J, Kosola S, Miettinen PJ, Raitakari O, Elovainio M, Raivio T, Hero M.   +12 more
europepmc   +1 more source

Adult‐Onset Effmann Type IIA2 Y‐Type Urethral Duplication Presenting as Unexplained Perineal Wetness: A Case Report Highlighting Diagnostic Pitfalls and Tailored Surgical Management

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Persistent perineal wetness in adults with normal standard imaging is uncommon and may indicate rare congenital anomalies such as urethral duplication. Case Presentation A man in his early 20s presented with a 3‐year history of intermittent perineal wetness of unknown origin.
Norichika Ueda, Tadahiko Kimura, Kentaro Takezawa, Taigo Kato, Koji Hatano, Yoichi Kakuta, Norio Nonomura, Atsunari Kawashima   +7 more
wiley   +1 more source

<i>SOX10</i> Mutation of Waardenburg Syndrome With Hypogonadism: A Report of 2 Cases. [PDF]

JCEM Case Rep
Yang Y, Zhang W, Zheng S, Jiang Y, Ye L, Sun S.   +5 more
europepmc   +1 more source

Growth in Paediatric Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Impaired linear growth is a common, clinically meaningful complication of paediatric inflammatory bowel disease (IBD), particularly Crohn's disease, arising from the combination of chronic intestinal inflammation, undernutrition, dysfunction of the growth hormone–insulin‐like growth factor‐1 axis, and iatrogenic effects such as glucocorticoid ...
Firas Rinawi, Séamus Hussey, Eileen Crowley, Dror S. Shouval, Iva Hojsak   +4 more
wiley   +1 more source

Comparative analysis of the bone age of wrist bones in Chinese children with different causes of short stature and central precocious puberty. [PDF]

Quant Imaging Med Surg
Liang T, Pan D, Wu D, Ruan C, Yuan L, Zeng H, Chen W.   +6 more
europepmc   +1 more source

Survival and Clinical Progression in Barth Syndrome: Insights From the Barth Syndrome Foundation's Database of 502 Affected Individuals

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Barth syndrome (BTHS; OMIM 302060) is an ultra‐rare, life‐limiting genetic disorder characterized by cardiomyopathy, skeletal muscle myopathy, neutropenia, gastrointestinal issues, and fatigue. Formal analyses of survival and clinical progression remain limited.
Kexin Fu, Yonglin Huang, Valerie Bowen, Katherine McCurdy, Reina B. Tan, Colin K. L. Phoon, Lindsay Marjoram, Alex Dahlen   +7 more
wiley   +1 more source

Complete androgen insensitivity syndrome presenting with bilateral adnexal masses and mixed gonadal histopathology. [PDF]

Arch Gynecol Obstet
Yildiz AG, Kurt A, Cengiz ID, Arslankoz S, Gultekin IB.   +4 more
europepmc   +1 more source

Adults With Acid Sphingomyelinase Deficiency Have Sustained Improvements in Clinical Outcomes With up to 5 Years of Olipudase Alfa Enzyme Replacement Therapy: ASCEND Trial Final Results

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Acid sphingomyelinase deficiency (ASMD) is a rare debilitating lysosomal storage disease resulting in multisystemic disease manifestations, significant disease burden, and early mortality for some individuals. Enzyme replacement therapy (ERT) with olipudase alfa (Xenpozyme) is the first disease‐specific treatment indicated for noncentral ...
Melissa P. Wasserstein, Carla E. Hollak, Antonio Barbato, Renata C. Gallagher, Roberto Giugliani, Norberto Bernardo Guelbert, Julia B. Hennermann, Takayuki Ikezoe, Robin Lachmann, Olivier Lidove, Paulina Mabe, Eugen Mengel, Maurizio Scarpa, Ebubekir Senates, Michel Tchan, Beth L. Thurberg, Jesus Villarrubia, Nicole M. Armstrong, Shashi Bhushan, Yong Kim, Monica Kumar   +20 more
wiley   +1 more source

Comparative Analysis of Dietary Patterns in Children With Phenylketonuria Phenotypes and Controls: Implications for Nutritional Status

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Individuals with phenylketonuria (PKU), caused by different variants of the phenylalanine hydroxylase gene, need to restrict their intake of phenylalanine. This study evaluated dietary patterns and physical activity levels in children with different PKU phenotypes compared to healthy controls. Eighty‐two children were recruited (22 classic PKU
Dolores Garcia‐Arenas, Aida Ormazabal, Paula Isern, Blanca Barrau‐Martinez, Arnau Gonzalez‐Rodriguez, Alba Tor‐Roca, Rafael Llorach, Jaume Campistol‐Plana, Mireia Urpi‐Sarda, Consortium PKU.cat.   +9 more
wiley   +1 more source