Results 101 to 110 of about 114,517 (262)

PRECOCIOUS PUBERTY

Ginekologia polska, 2011
Precocious puberty is an early sexual maturation before the age of 8 in case of girls and 9 in boys. There are two types: isosexual precocious puberty--characteristic are appropriate for the child's genetic and gonadal sex; and heterosexual precocious puberty--sexual characteristic are inappropriate for the genetic sex (feminizing syndrome in boys or ...
Grazyna, Jarzabek-Bielecka, Katarzyna, Warchoł-Biedermann, Elzbieta, Sowińska, Katarzyna, Wachowiak-Ochmańska   +3 more
  +5 more sources

Clinical spectrum of precocious puberty and its normal variants in children: insights from a seven-year review in a tertiary hospital, Calabar, Nigeria

Ibom Medical Journal
Context: Precocious puberty, clinically defined as the development of secondary sexual characteristics before 8 years of age in girls and 9 years in boys, represents a clinical spectrum that encompasses both pathological and non-pathological variants of
Eyong ME, Nsa EI, Uzomba CI, Eyong EM, Brown E, Ikobah JM, Etuk IS   +6 more
doaj   +1 more source

Association between MKRN3 and LIN28B polymorphisms and precocious puberty

BMC Genetics, 2018
Background The present study aimed to investigate the association between MKRN3 and LIN28B gene polymorphisms and precocious puberty in Korean boys and girls.
Bo Ram Yi, Hyun Jeong Kim, Hye Sook Park, Yoon Jeong Cho, Ju Young Kim, Jeong Yee, Jee Eun Chung, Joo Hee Kim, Kyung Eun Lee, Hye Sun Gwak   +9 more
doaj   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Association of Prenatal Urinary Concentrations of Phthalates and Bisphenol A and Pubertal Timing in Boys and Girls. [PDF]

, 2018
BackgroundAnimal studies suggest that phthalates and bisphenol A (BPA), endocrine-disrupting chemicals found in many consumer products, may impact the timing of puberty.ObjectivesWe aimed to determine the association of prenatal exposure to high ...
Berger, Kimberly, Calafat, Antonia M, Eskenazi, Brenda, Greenspan, Louise C, Harley, Kim G, Holland, Nina, Kogut, Katherine, Lustig, Robert H, Parra, Kimberly, Ye, Xiaoyun   +9 more
core   +1 more source

Endocrine disruptors and abnormalities of pubertal development [PDF]

, 2008
Onset and development of puberty is regulated by the neuroendocrine system. Population-based studies worldwide have observed secular trends towards earlier puberty development. These changes are apparently caused by environmental factors such as improved
Adair, Adair, Berg-Kelly, Blanck, Colon, DeCastro, Den Hond, Den Hond, Dunger, Gamba, Gladen, Gore, Grumbach, Guo, Hertz-Picciotto, Ibanez, Kaya, Klein, Krstevska-Konstantinova, Kubo, Kuhl, Lebrethon, Lee, Legler, Levine, Levy, Lewis, Marshall, Marshall, McKee, McLachlan, Mol, Naftolin, Ohtake, Parent, Patton, Petroff, Proos, Ramirez, Rasier, Rockett, Roselli, Rubin, Safe, Sagiv, Saiyed, Selevan, Singh, Skynner, Staessen, Styne, Teilmann, Tena-Sempere, Tena-Sempere, Terasawa, Traggiai, Vasiliu, Vinggaard, Wade, Warner, Wu, Wu, Zeinoaldini   +62 more
core   +2 more sources

Clinical Insights From a Case of Sifrim‐Hitz‐Weiss Syndrome With a CHD4 Variant: Expanding the Phenotypic Spectrum and Its Response to Growth Hormone Therapy

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1403-1410, June 2026.
ABSTRACT To enhance clinicians' understanding of Sifrim‐Hitz‐Weiss syndrome (SIHIWES), this study investigated the clinical phenotypes, genetic characteristics, and response to growth hormone therapy in a patient. A case of a patient with global developmental delay and distinctive facial features is presented.
Jianmei Zhang, Shuangzhong Chen, Guanping Dong, Suhong Yang, Ping Wang, Qiong Zhou, Pingping Wang   +6 more
wiley   +1 more source

Changes in sleep patterns in adolescents are more associated with pubertal indicators than age: A perfect storm with a dash of hormones

British Journal of Developmental Psychology, Volume 44, Issue 2, Page 437-453, June 2026.
Abstract As they become older, adolescents tend to prefer sleeping and rising later. Yet, it is still unclear if these sleep changes occur due to advancing age or because adolescents are more pubertally mature. This was investigated cross‐sectionally in a sample of 121 Brazilian 9‐to‐17‐year‐olds.
Yessica Alejandra Martínez‐Sánchez, Debora Cristina Hipolide, Rafaella Sales de Freitas, Sabine Pompeia   +3 more
wiley   +1 more source

Psychological assessment of mothers and their daughters at the time of diagnosis of precocious puberty [PDF]

, 2015
BACKGROUND: Concerns about psychological distress are often used to justify treatment of girls with precocious puberty, but there is little evidence to support these concerns.
Berenbaum, Sheri A., Bryk, Kristina, Didrick, Paula, Donahue, Kelly L., Eugster, Erica A., Schoelwer, Melissa J.   +5 more
core   +1 more source

Heterokairic Genes and the Eco‐Evo‐Devo of Timing

Evolution &Development, Volume 28, Issue 2, June 2026.
Heterokairic genes as the bridge (Heterokairic Pathways?): Heterokairic genes are heterochronic regulators whose activity is modulated by environmental conditions. External cues (e.g., temperature, nutrition, oxygen, density: yellow box) are sensed (yellow arrows) and converted into endocrine and metabolic signals (purple box and arrow into fish's ...
Leandro Lofeu, Ehsan Pashay Ahi
wiley   +1 more source