Results 81 to 90 of about 158,443 (246)

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Optimal therapy of pubertal disorders in precocious/early puberty

, 2001
. The possibility of progression of premature thelarche into precocious puberty, the pathogenesis of organic and idiopathic precocious puberty, the criteria for decision to treat and to stop treatment and the utility of an association with GH treatment ...
Tatò L., Savage M.O., Oostdijk W., Pasquino A.M., Raiola G., Saenger P., Tonini G., ANTONIAZZI, Franco, Voorhoeve P.G., Buzi F., Di Maio S., International Workshop on Management of Puberty for Optimum Auxological Results   +11 more
core   +1 more source

Gut microbiota alterations modulate high-fat diet-induced precocious puberty

Microbiology Spectrum
The link between gut microbiota and precocious puberty has garnered increasing attention; however, the underlying mechanisms remain poorly understood, and most existing studies are cross-sectional, making it difficult to capture the longitudinal changes ...
Nan Wu, Xin Jiang, Yihui Wang, Meilu Zhang, Min Yue, Fei Chen, Wei Wu, Yanan Liu, Qinghua Wang, Lei Zhang   +9 more
doaj   +1 more source

The prevalence of precocious puberty among children in Qufu City, Shandong Province, China, a population-based study

Frontiers in Endocrinology, 2022
ObjectiveWe sought to investigate the prevalence of precocious puberty in children aged 6–10 years in Qufu City, Shandong Province, China.MethodsA total of 5,169 primary school students from grades 1–3 were recruited by population-based multi-stage ...
Yawen Zhang, Jianmin Ni, Lei Zhang, Tingting Yu, Tingting Yu, Xiaoqing Li, Xiaoqing Li, Peng Xue, Peng Xue, Yifan Liu, Bo Gao, Xinwen Xue, Huijun Kong, Shijian Liu, Shijian Liu   +14 more
doaj   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature

BMC Endocrine Disorders, 2023
Background The pineal lesion affecting melatonin is a rare cause of central precocious puberty by decreasing the inhibition of hypothalamic–pituitary–gonadal axis.
Han Chen, Cai-Yan Mo, Li-yong Zhong
doaj   +1 more source

Diagnostic Yield of Brain MRI in Pediatric Short Stature: Hypothalamic–Pituitary Lesions and Incidental Findings in Real‐World Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Background Brain MRI is widely performed in children with short stature or suspected growth hormone deficiency(GHD) to exclude hypothalamic–pituitary (HP) pathology, yet its diagnostic yield in routine practice is uncertain. We aimed to evaluate the prevalence, clinical significance, and distribution of HP and extrahypothalamic abnormalities ...
Mustafa Zubeidat, Tamer Sobeh, Shai Shrot   +2 more
wiley   +1 more source

Pathogenicity of NUSAP1 Variants Is Defined by NMD‐Escape: Evidence From Two Novel Cases and Systematic Population‐Based Variant Analysis

Clinical Genetics, EarlyView.
Heterozygous de novo nonsense variants in the penultimate and last exons of NUSAP1 were identified in two unrelated individuals, predicted to escape NMD. In population data, nonsense variants were observed in exons 1–9 (of 11) in NUSAP1 but were absent from its 3′‐terminal region.
Maureen Jacob, Susann Badmann, Stefania Bigoni, Maria Iascone, Ilaria Vivaldi, Katharina Mayerhanser, Robert Kopajtich, Holger Prokisch, Cristina Forest, Sebastian Eck, Michael Zech, Elisabeth Graf, Matias Wagner, Juliane Winkelmann, Theresa Brunet, Melanie Brugger   +15 more
wiley   +1 more source

Ovarian cysts and tumors as the cause of isosexual pseudoprecocious puberty [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2006
Introduction. Precocious puberty in girls is generally defined as appearance of secondary sexual characteristics before eight years of age. Menarche before the ninth birthday may serve as an additional criterion.
Mitrović Katarina, Zdravković Dragan, Milenković Tatjana, Sedlecki Katarina, Stanković Zoran   +4 more
doaj   +1 more source

Genetic and Phenotypic Correlations Among Growth, Disease Occurrence, and Reproductive Performance From Calf to Heifer in Girolando Dairy Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The Girolando breed, a cross between Holstein (Bos taurus) and Gir (Bos indicus), is the primary choice for dairy production in Brazilian tropical regions, as it combines high productive potential with adaptation to the tropical environment.
Laura B. da C. Pereira, Viviane A. Ligori, Hinayah R. de Oliveira, Eula R. Carrara, Carolina A. de S. D. Muniz, Edson L. de A. Ribeiro, Lenira E. F. Zadra   +6 more
wiley   +1 more source