Results 81 to 90 of about 114,517 (262)

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng   +9 more
wiley   +1 more source

Gut microbiota alterations modulate high-fat diet-induced precocious puberty

open access: yesMicrobiology Spectrum
The link between gut microbiota and precocious puberty has garnered increasing attention; however, the underlying mechanisms remain poorly understood, and most existing studies are cross-sectional, making it difficult to capture the longitudinal changes ...
Nan Wu   +9 more
doaj   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

open access: yesJCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista   +5 more
wiley   +1 more source

Risky,early, controversial. Puberty in medical discourses [PDF]

open access: yes, 2015
This article comes within the compass of a research program (entitled CorAge. Bodily Experiences and AgePassages among 9e13 year-olds (ANR-09-ENFT-017) conducted between 2009 and 2013 about the emergence of a \u201cnew\u201d age in life ...
Cozzi, D, Vinel, V.
core   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

Experience with the Histrelin Implant in Pediatric Patients [PDF]

open access: yes, 2015
The histrelin implant has emerged as a therapeutic option for the treatment of central precocious puberty that has been favorably received by patients and providers.
Eugster, Erica A.
core   +1 more source

Precocious puberty in girls

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Precocious puberty in girls can be due to number of factors of which idiopathic central precocious puberty is the most common etiology. Here, we describe 3 cases of precocious puberty where the first case had premature thelarche in the background history
Sachin Chittwar, Shivprakash, A C Ammini
doaj   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

open access: yesAndrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby   +10 more
wiley   +1 more source

Fulvestrant treatment of precocious puberty in girls with McCune-Albright syndrome [PDF]

open access: yes, 2012
BACKGROUND: McCune-Albright Syndrome (MAS) is usually characterized by the triad of precocious puberty (PP), fibrous dysplasia, and café au lait spots. Previous treatments investigated for PP have included aromatase inhibitors and the estrogen receptor ...
Charles Sultan   +6 more
core   +1 more source

Ovarian cysts and tumors as the cause of isosexual pseudoprecocious puberty [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2006
Introduction. Precocious puberty in girls is generally defined as appearance of secondary sexual characteristics before eight years of age. Menarche before the ninth birthday may serve as an additional criterion.
Mitrović Katarina   +4 more
doaj   +1 more source

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