Results 81 to 90 of about 114,517 (262)
Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng +9 more
wiley +1 more source
Gut microbiota alterations modulate high-fat diet-induced precocious puberty
The link between gut microbiota and precocious puberty has garnered increasing attention; however, the underlying mechanisms remain poorly understood, and most existing studies are cross-sectional, making it difficult to capture the longitudinal changes ...
Nan Wu +9 more
doaj +1 more source
Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista +5 more
wiley +1 more source
Risky,early, controversial. Puberty in medical discourses [PDF]
This article comes within the compass of a research program (entitled CorAge. Bodily Experiences and AgePassages among 9e13 year-olds (ANR-09-ENFT-017) conducted between 2009 and 2013 about the emergence of a \u201cnew\u201d age in life ...
Cozzi, D, Vinel, V.
core +1 more source
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas +128 more
wiley +1 more source
Experience with the Histrelin Implant in Pediatric Patients [PDF]
The histrelin implant has emerged as a therapeutic option for the treatment of central precocious puberty that has been favorably received by patients and providers.
Eugster, Erica A.
core +1 more source
Precocious puberty in girls can be due to number of factors of which idiopathic central precocious puberty is the most common etiology. Here, we describe 3 cases of precocious puberty where the first case had premature thelarche in the background history
Sachin Chittwar, Shivprakash, A C Ammini
doaj +1 more source
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Fulvestrant treatment of precocious puberty in girls with McCune-Albright syndrome [PDF]
BACKGROUND: McCune-Albright Syndrome (MAS) is usually characterized by the triad of precocious puberty (PP), fibrous dysplasia, and café au lait spots. Previous treatments investigated for PP have included aromatase inhibitors and the estrogen receptor ...
Charles Sultan +6 more
core +1 more source
Ovarian cysts and tumors as the cause of isosexual pseudoprecocious puberty [PDF]
Introduction. Precocious puberty in girls is generally defined as appearance of secondary sexual characteristics before eight years of age. Menarche before the ninth birthday may serve as an additional criterion.
Mitrović Katarina +4 more
doaj +1 more source

