Results 61 to 70 of about 12,066 (178)

Conversion Practices in Eating Disorder Treatment: A Lived Experience Narrative

Journal of Psychiatric and Mental Health Nursing, EarlyView.
ABSTRACT Background and Aim Conversion practices (sometimes referred to as ‘conversion therapy’) refer to interventions that aim to change a person's sexual orientation or gender identity. While these are often associated with faith‐based settings, they can also occur in secular healthcare contexts.
Cody Spadaccini, Kai Schweizer
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Complex Genetic Architecture in RASopathies: Constitutional PTPN11 and Mosaic RIT1 Pathogenic Variants Underlying Severe Noonan Syndrome With Adult‐Onset Acute Myeloid Leukemia

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1879-1883, August 2026.
ABSTRACT Noonan syndrome (NS) is a genetically heterogeneous disorder characterized by a broad spectrum of clinical features resulting from dysregulation of the RAS/MAPK pathway. Although complex genotypes are increasingly recognized in NS, cases harboring two distinct pathogenic variants in different NS genes remain extremely rare.
Francesco Prevedello, Dario Seif Ali, Chiara Piccolo, Chiara Rigon, Monica Forzan, Elena Tacchetto, Roberta Palmitessa, Davide Calosci, Leonardo Salviati, Carmela Gurrieri, Eva Trevisson   +10 more
wiley   +1 more source

The Clinical Phenotype and Genetic Analysis of Monogenic Non Syndromic Obesity Caused by MC4R Gene Variation

Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
A novel MC4R mutation (c.185A > G) was identified in a 10‐year‐old girl with severe obesity and hyperinsulinemia. Retrospective analysis of 64 pediatric cases revealed that mutation location influences BMI, modulated by underlying disease status, demonstrating that the genotype–phenotype relationship in MC4R‐associated obesity is clinically context ...
Xin Li, Xiaotian Wang, Xin Liu, Shuping Wang, Wentao Yang   +4 more
wiley   +1 more source

Idiopathic Central Precocious Puberty Associated with 11 Mb De Novo Distal Deletion of the Chromosome 9 Short Arm

Case Reports in Genetics, 2013
We report a girl with a de novo distal deletion of 9p affected by idiopathic central precocious puberty and intellectual disability. Genome-wide array-CGH revealed a terminal deletion of about 11 Mb, allowing to define her karyotype as 46; XX, del(9)(p23-
Mariangela Cisternino, Erika Della Mina, Laura Losa, Alexandra Madè, Giulia Rossetti, Lorenzo Andrea Bassi, Giovanni Pieri, Baran Bayindir, Jole Messa, Orsetta Zuffardi, Roberto Ciccone   +10 more
doaj   +1 more source

Gut flora influences the hypothalamic-gonadal axis to regulate the pathogenesis of obesity-associated precocious puberty

Scientific Reports
The prevalence of obesity-associated precocious puberty is gradually increasing, but the relationship between gut flora and obesity-associated precocious puberty remains unclear.We analysed the gut flora characteristics of a clinical sample of 30 girls ...
Ying Qian, Xiaodan Fang, Yan Chen, Mingxing Ding, Min Gong   +4 more
doaj   +1 more source

Precocious and Early Central Puberty in Children With Pre-existing Medical Conditions: A Single Center Study

Frontiers in Pediatrics, 2019
Background: Precocious and early puberty are reported findings in children with pre-existing medical conditions including certain syndromes. Series pertaining to such situations are limited.Methods: A retrospective, single-center study was conducted on ...
Sarah Winter, Adélaïde Durand, Raja Brauner   +2 more
doaj   +1 more source

Serum vitamin D levels in girls with central precocious puberty

Pharmaceutical and Biomedical Research, 2018
Precocious puberty can cause several adverse effects on final growth and social behavior in girls. Recent studies showed that low serum level of vitamin D might be associated with precocious puberty.
Mohammadreza Rafati, Daniel Zamanfar, Seyedeh-Nesa RezaeianShiadeh, Fatemeh Faramarzi, Mohsen Aarabi, Hamid Rayati Damavandi   +5 more
doaj  

Alterations in the gut microbiota community are associated with childhood obesity and precocious puberty

BMC Microbiology
Objective To explore the distribution and differences in the intestinal microbiota in girls with obesity-related precocious puberty and the relationship between intestinal microbiota and obesity-related precocious puberty.
Li Wang, Qin Yi, Hao Xu, Huiwen Liu, Bin Tan, Hongrong Deng, Yunxia Chen, Rui Wang, Fang Tang, Xinran Cheng, Jing Zhu   +10 more
doaj   +1 more source

Central Precocious Puberty as a Complication of Therapy with Adrenocorticotropin (ACTH) and an Aromatase Inhibitor for Refractory Nephrotic Syndrome

Case Reports in Pediatrics, 2019
Glucocorticoids are typically prescribed for the treatment of idiopathic nephrotic syndrome of childhood. In selected patients with refractory focal segmental glomuerulosclerosis (FSGS), adrenocorticotropin (ACTH) can be used to induce remission and ...
Sungeeta Agrawal, Robert Gensure, Lawrence Milner, Julie Nicoletta, Abdollah Sadeghi-Nejad   +4 more
doaj   +1 more source