Results 51 to 60 of about 53,471 (177)

The prevalence of precocious puberty among children in Qufu City, Shandong Province, China, a population-based study

Frontiers in Endocrinology, 2022
ObjectiveWe sought to investigate the prevalence of precocious puberty in children aged 6–10 years in Qufu City, Shandong Province, China.MethodsA total of 5,169 primary school students from grades 1–3 were recruited by population-based multi-stage ...
Yawen Zhang, Jianmin Ni, Lei Zhang, Tingting Yu, Tingting Yu, Xiaoqing Li, Xiaoqing Li, Peng Xue, Peng Xue, Yifan Liu, Bo Gao, Xinwen Xue, Huijun Kong, Shijian Liu, Shijian Liu   +14 more
doaj   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Gut microbiota alterations modulate high-fat diet-induced precocious puberty

Microbiology Spectrum
The link between gut microbiota and precocious puberty has garnered increasing attention; however, the underlying mechanisms remain poorly understood, and most existing studies are cross-sectional, making it difficult to capture the longitudinal changes ...
Nan Wu, Xin Jiang, Yihui Wang, Meilu Zhang, Min Yue, Fei Chen, Wei Wu, Yanan Liu, Qinghua Wang, Lei Zhang   +9 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

The Risk Factors of Puberty Precocious in Girls: Is the Condition Related with Polychlorobiphenyls? [PDF]

, 2021
Aim:Our aim was investigate the effect of polychlorobifenyls (PCBs) and other factors on puberty precocious (PP) in girls were diagnosed with idiopatic PP and premature thelarche (PT).Materials and Methods:The study group included 50 girls aged between 2-
Şükran Darcan, Ruhsar Damla Gökşen, Samim Özen, Raziye Burcu Güven Bilgin, Özlem Korkmaz   +4 more
core   +1 more source

Optimal therapy of pubertal disorders in precocious/early puberty

, 2001
. The possibility of progression of premature thelarche into precocious puberty, the pathogenesis of organic and idiopathic precocious puberty, the criteria for decision to treat and to stop treatment and the utility of an association with GH treatment ...
Tatò L., Savage M.O., Oostdijk W., Pasquino A.M., Raiola G., Saenger P., Tonini G., ANTONIAZZI, Franco, Voorhoeve P.G., Buzi F., Di Maio S., International Workshop on Management of Puberty for Optimum Auxological Results   +11 more
core   +1 more source

Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature

BMC Endocrine Disorders, 2023
Background The pineal lesion affecting melatonin is a rare cause of central precocious puberty by decreasing the inhibition of hypothalamic–pituitary–gonadal axis.
Han Chen, Cai-Yan Mo, Li-yong Zhong
doaj   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

Journal of Adolescence, EarlyView.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino, Samantha Dockray, Maria Dempsey, Eleonora Tomei   +3 more
wiley   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

New PMCT multi‐indicator ossification standards for age estimation of the knee in modern Australian and North American children

Journal of Forensic Sciences, EarlyView.
Abstract Skeletal age estimation is crucial to medicolegal work, aiding subadult identification, and living age assessments in legal contexts. This study aims to document the ontogeny of knee skeletal indicators on post‐mortem computed tomography (PMCT), and quantify interpopulation variation between modern American and Australian children.
Taliah Swart, Clair Alston‐Knox, Samantha K. Rowbotham, Soren Blau, Nicolene Lottering   +4 more
wiley   +1 more source