Results 41 to 50 of about 12,066 (178)

The prevalence of precocious puberty among children in Qufu City, Shandong Province, China, a population-based study

open access: yesFrontiers in Endocrinology, 2022
ObjectiveWe sought to investigate the prevalence of precocious puberty in children aged 6–10 years in Qufu City, Shandong Province, China.MethodsA total of 5,169 primary school students from grades 1–3 were recruited by population-based multi-stage ...
Yawen Zhang   +14 more
doaj   +1 more source

Retrospective Analysis of T2‐Hyperintense Lesions in Children With Neurofibromatosis Type 1

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective The aim of this study is to determine whether a previously reported three‐tiered classification scheme for T2‐hyperintense brain lesions in children with neurofibromatosis type 1 (NF1) was associated with distinct radiographic or clinical characteristics after 10 years of real‐world follow‐up data were obtained.
Ariel B. Brickler   +4 more
wiley   +1 more source

Gut microbiota alterations modulate high-fat diet-induced precocious puberty

open access: yesMicrobiology Spectrum
The link between gut microbiota and precocious puberty has garnered increasing attention; however, the underlying mechanisms remain poorly understood, and most existing studies are cross-sectional, making it difficult to capture the longitudinal changes ...
Nan Wu   +9 more
doaj   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary   +59 more
wiley   +1 more source

Maternal and infant gut microbiome

open access: yesiMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang   +25 more
wiley   +1 more source

Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature

open access: yesBMC Endocrine Disorders, 2023
Background The pineal lesion affecting melatonin is a rare cause of central precocious puberty by decreasing the inhibition of hypothalamic–pituitary–gonadal axis.
Han Chen, Cai-Yan Mo, Li-yong Zhong
doaj   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino   +3 more
wiley   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

open access: yesJCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista   +5 more
wiley   +1 more source

Exploring the Mechanistic Interplay between Gut Microbiota and Precocious Puberty: A Narrative Review

open access: yesMicroorganisms
The gut microbiota has been implicated in the context of sexual maturation during puberty, with discernible differences in its composition before and after this critical developmental stage.
Min Yue, Lei Zhang
doaj   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

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