Results 41 to 50 of about 53,471 (177)

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young, Armelle Pindon, Maggie R. Brand, Kate Wears, Katherine H. Young, Alyssa Mendel, Michael J. Lyons   +6 more
wiley   +1 more source

Abdominal imaging in precocious puberty in girls [PDF]

Precocious puberty in girls is defined by the appearance of secondary sex characteristics before the age of 8 years. Precocious puberty is either peripheral or central. In most cases, the cause of central precocious puberty is unknown.
Sofia, Carmelo, Napolitano, Marcello, Ključevšek, Damjana, Bruno, Costanza, Smets, Anne M., Lobo, Maria-Luisa   +5 more
core   +2 more sources

Precocious puberty in children [PDF]

International Journal of Pediatric Endocrinology, 2013
To determine the etiology of precocious puberty in children and to compare the clinical and laboratory parameters of central and peripheral precocious puberty.Cross-sectional study.Endocrine Clinic at National Institute of Child Health, Karachi, from January 2009 to December 2011.Children presenting with precocious puberty were included.
Atta, Irum, laghari, Taj, Khan, Yasir, Lone, Saira, Ibrahim, Mohsina, Raza, Jamal   +5 more
openaire   +2 more sources

Developmental differences in cortical bone structure in chimpanzee and human femora reflect early locomotor independence in humans

The Anatomical Record, EarlyView.
Abstract The cortical bone structure of long bone diaphyses changes throughout growth via skeletal modeling and has important implications for bone strength and structural integrity. Ontogenetic trends in diaphyseal structure have been identified in both chimpanzees and humans but it is not yet clear how these trends compare given notable differences ...
Karen R. Swan, Rachel Ives, Zewdi J. Tsegai, Louise T. Humphrey   +3 more
wiley   +1 more source

Causes and Types of Precocious Puberty in North-West Iran [PDF]

, 2013
Objective: Precocious puberty is of concern because of the underlying disorders, the short adult stature, and the psychosocial difficulties. This study was carried out in order to evaluate the characteristics of children referred to pediatric ...
Shiva, Siamak, Shiva, Shadi, Fayyazi, Afshin, Melikian, Armen   +3 more
core   +2 more sources

Dietary pattern and precocious puberty risk in Chinese girls: a case-control study

Nutrition Journal
Background The role of dietary intake on precocious puberty remains unclear. This study aimed to investigate the association between the amount and frequency of dietary intake and the risk of precocious puberty in Chinese girls.
Qiuyun Gu, Youmei Wu, Zhuowei Feng, Yimeng Chai, Shan Hou, Zhiping Yu, Xiuhua Shen   +6 more
doaj   +1 more source

Guilt, Uncertainty, Education Needs, and Knowledge of Mothers With Children Experiencing Precocious Puberty

Global Pediatric Health, 2022
Introduction. Childhood illnesses not only affect the child, but also the family members. Objective. The purpose of this study was to investigate the guilt, uncertainty, education needs, and knowledge of mothers with children experiencing precocious ...
Hye Young Ahn RN, PhD, Kyung Hee Yoo RN, MSN, Mi Ryeong Song RN, PhD   +2 more
doaj   +1 more source

Retrospective Analysis of T2‐Hyperintense Lesions in Children With Neurofibromatosis Type 1

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective The aim of this study is to determine whether a previously reported three‐tiered classification scheme for T2‐hyperintense brain lesions in children with neurofibromatosis type 1 (NF1) was associated with distinct radiographic or clinical characteristics after 10 years of real‐world follow‐up data were obtained.
Ariel B. Brickler, Manu S. Goyal, Robert C. McKinstry, David H. Gutmann, Jennifer L. Griffith   +4 more
wiley   +1 more source

Sonography of abdominal organs in precocious puberty in girls [PDF]

, 2013
Precocious puberty constitutes a significant clinical problem due to psychological implications and health concerns as well as consequences associated with girls’ fertility.
Maciej Mazgaj, Mazgaj, Maciej
core