Results 31 to 40 of about 114,517 (262)

True precocious puberty following treatment of a Leydig cell tumour: two case reports and literature review

open access: yesFrontiers in Pediatrics, 2015
Leydig cell testicular tumours are a rare cause of precocious pseudopuberty in boys. Surgery is the main therapy and shows good overall prognosis. The physical signs of precocious puberty are expected to disappear shortly after surgical removal of the ...
Alberto eVerrotti   +5 more
doaj   +1 more source

Is precocious puberty linked to hypothalamic expression of arginine-phenylalanine-amide-related peptide? [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
The up-regulator regulation and down-regulator regulation of gonadotropin-releasing hormone (GnRH) in central precocious puberty is not yet known. However, recent advances in neuroendocrinology have shown the controlling role of arginine-phenylalanine ...
Yuanyuan He, Wen Sun, Jian Yu
doaj   +1 more source

Grey matter volume correlates with virtual water maze task performance in boys with androgen excess [PDF]

open access: yes, 2011
Major questions remain about the specific role of testosterone in human spatial navigation. We tested 10 boys (mean age 11.65 years) with an extremely rare disorder of androgen excess (Familial Male Precocious Puberty, FMPP) and 40 healthy boys (mean age
Cornwell, BR   +7 more
core   +2 more sources

Treatment of Peripheral Precocious Puberty [PDF]

open access: yes, 2015
There are many etiologies of peripheral precocious puberty (PPP) with diverse manifestations resulting from exposure to androgens, estrogens, or both. The clinical presentation depends on the underlying process and may be acute or gradual.
Eugster, Erica A., Schoelwer, Melissa
core   +1 more source

Lipid profile in girls with precocious puberty: a systematic review and meta-analysis

open access: yesBMC Endocrine Disorders, 2023
Objective Many studies have investigated the impact of precocious puberty on cardiovascular disease (CVD) outcomes and the association between lipid profile levels and precocious puberty. However, the results have been inconsistent.
Mei Jiang   +3 more
doaj   +1 more source

Childhood obesity and central precocious puberty

open access: yesFrontiers in Endocrinology, 2022
Childhood obesity is a major public health problem worldwide, and the relationship between obesity and central precocious puberty has long been confirmed, however, the mechanisms underlying this association remain elusive.
Li Shi, Zhiyan Jiang, Li Zhang
semanticscholar   +1 more source

Evo-devo of human adolescence: beyond disease models of early puberty [PDF]

open access: yes, 2013
Despite substantial heritability in pubertal development, much variation remains to be explained, leaving room for the influence of environmental factors to adjust its phenotypic trajectory in the service of fitness goals.
A Templeton   +69 more
core   +2 more sources

Postnatal Feeding With a Fat Rich Diet Induces Precocious Puberty Independent of Body Weight, Body Fat, and Leptin Levels in Female Mice

open access: yesFrontiers in Endocrinology, 2019
Puberty generally occurs when an individual has stored a sufficient amount of energy. Previous reports have shown that postnatal overfeeding, induced by a small litter size or maternal high fat diet (HFD) feeding during gestation and lactation increases ...
Rahim Ullah   +8 more
doaj   +1 more source

The Congenital and Acquired Mechanisms Implicated in the Etiology of Central Precocious Puberty.

open access: yesEndocrine reviews, 2022
The etiology of central precocious puberty (CPP) is multiple and heterogeneous, including congenital and acquired causes that can be associated with structural or functional brain alterations.
V. Brito   +8 more
semanticscholar   +1 more source

Substance P regulates puberty onset and fertility in the female mouse [PDF]

open access: yes, 2015
Puberty is a tightly regulated process that leads to reproductive capacity. Kiss1 neurons are crucial in this process by stimulating GnRH, yet how Kiss1 neurons are regulated remains unknown. Substance P (SP), an important neuropeptide in pain perception,
Carroll, R.S.   +7 more
core   +1 more source

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