Results 231 to 240 of about 160,231 (306)

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Connecting prenatal exposure to paracetamol with postnatal reproductive development: a first of its kind study in reproductive toxicology. [PDF]

Hum Reprod Open
De Geyter C.
europepmc   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

Cranial MRI in Girls With Central Precocious Puberty: Clinical Characteristics and Predictors of Abnormal Findings. [PDF]

Saudi Med J
Al Juraibah FN, Alharbi MM, Alharbi RD, Albaraki JS, AlDharman SS, Alghamdi HA, Yenugadhati N, Alhammad AI, Almutair AN, Al Alwan IA.   +9 more
europepmc   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Precocious puberty in boys: current insights into etiology, genetic advances, and environmental factors. [PDF]

Front Endocrinol (Lausanne)
Amodeo ME, Mirra G, Deodati A, Cianfarani S.   +3 more
europepmc   +1 more source

Correction: Central precocious puberty as the initial manifestation of multisystem involvement caused by <i>de novo</i> heterozygous <i>KMT2B</i> mutation and STS hemizygous deletion: a case report. [PDF]

Front Endocrinol (Lausanne)
Feng Y, Yang L, Xu QB, Cao LF.
europepmc   +1 more source

Timing and tempo of pubertal development and self-harm and suicidality in adolescents: a follow-up study in the Danish National Birth Cohort

Thomsen AML, Ernst A, Strandberg-Larsen K, Rask CU, Madsen T, Gaml-Sørensen A, Benson TE, Arah OA, Ramlau-Hansen CH.   +8 more
europepmc   +1 more source