Results 61 to 70 of about 286,655 (306)

Nutrition and pubertal development

open access: yesIndian Journal of Endocrinology and Metabolism, 2014
Nutrition is one of the most important factors affecting pubertal development. Puberty entails a progressive nonlinear process starting from prepubescent to full sexual maturity through the interaction and cooperation of biological, physical, and ...
Ashraf Soliman   +2 more
doaj   +1 more source

Juvenile granulosa cell tumor in a nine year old

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Pediatric granulosa cell tumors of the ovary are rare functional neoplasms causing secondary precocious puberty. The tumor possesses significant diagnostic challenge when occurs in a patient approaching puberty due to masking of symptoms.
Syed Waqas Ali   +4 more
doaj   +1 more source

Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand. [PDF]

open access: yes, 2019
OBJECTIVE: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV. DESIGN: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand.
Abou-Rayyah, ACM   +436 more
core   +4 more sources

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

open access: yesAdvanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues   +6 more
wiley   +1 more source

Testosterone Trajectories and Reference Ranges in a Large Longitudinal Sample of Male Adolescents [PDF]

open access: yes, 2014
Pubertal dynamics plays an important role in physical and psychological development of children and adolescents. We aim to provide reference ranges of plasma testosterone in a large longitudinal sample.
Ingle, Suzanne M   +6 more
core   +4 more sources

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

open access: yesAdvanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu   +12 more
wiley   +1 more source

The Role Of School Counselors To Helping Student in Puberty Through The Collaborative Paradigm

open access: yesEnlighten, 2020
Adolescent is one of the stages in human life that is very critical, because it is a stage of transition from childhood to adulthood. At this stage a lot of changes occur in adolescents, such as physical, emotional and social changes.
Ramdani Ramdani   +4 more
doaj   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

open access: yesAdvanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao   +8 more
wiley   +1 more source

Influence of HFD-induced precocious puberty on neurodevelopment in mice

open access: yesNutrition & Metabolism, 2021
Background Precocious puberty is frequently associated with obesity, which will lead to long-term effects, especially on growth and reproduction. However, the effect of precocious puberty on children's neurodevelopment is still unknown.
Tingbei Bo   +5 more
doaj   +1 more source

Genome-wide identification of QTL for age at puberty in gilts using a large intercross F population between White Duroc × Erhualian [PDF]

open access: yes, 2008
Puberty is a fundamental development process experienced by all reproductively competent adults, yet the specific factors regulating age at puberty remain elusive in pigs. In this study, we performed a genome scan to identify quantitative trait loci (QTL)
Guo Yuanmei   +8 more
core   +3 more sources

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