Results 41 to 50 of about 160,231 (306)

Temporal characterization of the insulin resistance during puberty in mice

open access: yesEndocrine Regulations, 2021
Objectives. The onset of puberty in humans is followed by an increase in insulin resistance and this transient phenomenon decreases at the end of the puberty. However, the insulin resistance during puberty has not been described in mice.
Teixeira Pryscila D.S.   +2 more
doaj   +1 more source

Puberty and its Significance as Perceived by Prepubescents in Croatia

open access: yesMagistra Iadertina, 2021
Prepubescent children need to be prepared for puberty in an appropriate manner including all related associations and contexts. Children should learn the required knowledge before its onset—when they are in primary school.
Miluše Rašková   +2 more
doaj   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

open access: yesAdvanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang   +4 more
wiley   +1 more source

Etiology of precocious puberty, 10 years study in Endocrine Reserch Centre (Firouzgar), Tehran [PDF]

open access: yesIranian Journal of Reproductive Medicine, 2012
Background: Precocious puberty, as early physical development and low final height might lead to psychosocial problems.Objective: To evaluate etiology and clinical feature of precocious puberty in a cohort of Iranian children.Materials and Methods: In ...
Fatemeh Safari   +2 more
doaj  

Leptin and puberty [PDF]

open access: yesArchives of Disease in Childhood, 2000
Our knowledge of the potential genetic link between fat metabolism and the reproductive axis dates back to the 1950s when the obese ( ob/ob ) mouse strain was first described. These mice were not only distinctly hyperphagic and rapidly developed obesity associated with hyperglycaemia and insulin resistance, but they were also infertile.1 It was not ...
Clayton, PE; id_orcid 0000-0003-1225-4537   +1 more
openaire   +3 more sources

Etiology and Clinical Features of Isosexual Precocious Puberty in Taiwanese Girls: Twenty-Three Years' Experience in National Taiwan University Hospital

open access: yes, 2011
The aim of this study was to elucidate the etiology and clinical features of Taiwanese girls with isosexual precocious puberty. 460 girls with precocious puberty were enrolled in this study.
李正婷;童怡靖;蔡文友   +1 more
core   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

open access: yesAdvanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao   +27 more
wiley   +1 more source

Frequency of Delayed Puberty in Boys with Contemporary Management of Duchenne Muscular Dystrophy

open access: yesJCRPE
INTRODUCTION: Delayed puberty is thought to be common in boys with Duchenne muscular dystrophy (DMD) treated with long term oral glucocorticoid. The aim of this study was to report the frequency of delayed puberty in DMD from examination by a paediatric ...
Sarah McCarrison   +6 more
doaj   +1 more source

Nutrition and pubertal development

open access: yesIndian Journal of Endocrinology and Metabolism, 2014
Nutrition is one of the most important factors affecting pubertal development. Puberty entails a progressive nonlinear process starting from prepubescent to full sexual maturity through the interaction and cooperation of biological, physical, and ...
Ashraf Soliman   +2 more
doaj   +1 more source

Pubertal timing and growth influences cardiometabolic risk factors in adult males and females. [PDF]

open access: yes, 2011
OBJECTIVE: Early pubertal onset in females is associated with increased risk for adult obesity and cardiovascular disease, but whether this relationship is independent of preceding childhood growth events is unclear.
Widen, Elisabeth   +18 more
core   +1 more source

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