Results 61 to 70 of about 160,231 (306)

Single‐Cell Insights Into Pathogenic Profile of Orchitis and SREBP2‐Associated Cholesterol Dysregulation in Spermatogenic Failure

open access: yesAdvanced Science, EarlyView.
A first single‐cell atlas of human orchitis reveals coordinated germ‐cell loss, somatic niche dysfunction, and immune‐metabolic remodeling. Aberrant SREBP2 activation in testicular somatic cells emerges as a central pathogenic node, while Fatostatin‐mediated inhibition of the SREBP pathway improves spermatogenesis, fibrosis, and lipid accumulation in a
Yanlin Tang   +16 more
wiley   +1 more source

Juvenile granulosa cell tumor in a nine year old

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Pediatric granulosa cell tumors of the ovary are rare functional neoplasms causing secondary precocious puberty. The tumor possesses significant diagnostic challenge when occurs in a patient approaching puberty due to masking of symptoms.
Syed Waqas Ali   +4 more
doaj   +1 more source

iMatter: Teaching about Puberty, Gender, and Fairness

open access: yes, 2017
The Population Council created iMatter as an integrated approach to teach younger adolescents about gender, puberty, and fairness. This iMatter Curriculum ordering page includes instructions for ordering all items.
Haberland, Nicole, Rogow, Debbie
core   +1 more source

Internet use and adolescent development: A conceptual model integrating behavioral and contextual theories

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract In the digital era, adolescent development is deeply embedded in the cyber environment. Despite ongoing debate on the benefits and/or risks that Internet use brings to adolescents in empirical studies, conceptual and theoretical discussion on the influences of the intensity and modalities of Internet use is peripheral.
Linxiao Zhang   +3 more
wiley   +1 more source

The Role Of School Counselors To Helping Student in Puberty Through The Collaborative Paradigm

open access: yesEnlighten, 2020
Adolescent is one of the stages in human life that is very critical, because it is a stage of transition from childhood to adulthood. At this stage a lot of changes occur in adolescents, such as physical, emotional and social changes.
Ramdani Ramdani   +4 more
doaj   +1 more source

Nonlinear growth generates age changes in the moments of the frequency distribution: the example of height in puberty [PDF]

open access: yes, 2008
Higher moments of the frequency distribution of child height and weight change with age, particularly during puberty, though why is not known. Our aims were to confirm that height skewness and kurtosis change with age during puberty, to devise a model to
Cortina-Borja, M   +4 more
core  

Spinal Involvement in Charge Syndrome: Implications for Management

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT CHARGE syndrome (OMIM #214800) is an autosomal dominant disorder caused by mutations in the CHD7 gene in most cases. Although originally defined by the CHARGE acronym (coloboma, heart defects, choanal atresia, growth restriction, genital hypoplasia, and ear anomalies), the recognized phenotype has expanded considerably to include highly ...
Adriana Gomes   +5 more
wiley   +1 more source

Influence of HFD-induced precocious puberty on neurodevelopment in mice

open access: yesNutrition & Metabolism, 2021
Background Precocious puberty is frequently associated with obesity, which will lead to long-term effects, especially on growth and reproduction. However, the effect of precocious puberty on children's neurodevelopment is still unknown.
Tingbei Bo   +5 more
doaj   +1 more source

Sonography of abdominal organs in precocious puberty in girls [PDF]

open access: yes, 2013
Precocious puberty constitutes a significant clinical problem due to psychological implications and health concerns as well as consequences associated with girls’ fertility.
Maciej Mazgaj, Mazgaj, Maciej
core  

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto   +5 more
wiley   +1 more source

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