Results 61 to 70 of about 291,425 (313)

Temporal characterization of the insulin resistance during puberty in mice

Endocrine Regulations, 2021
Objectives. The onset of puberty in humans is followed by an increase in insulin resistance and this transient phenomenon decreases at the end of the puberty. However, the insulin resistance during puberty has not been described in mice.
Teixeira Pryscila D.S., Tavares Mariana R., Jose Donato   +2 more
doaj   +1 more source

Donor gender does not affect liver transplantation outcome in children [PDF]

, 1990
The liver is recognized as a sex hormone-responsive organ. Gender-specific differences in liver function are known to exist. Recently, a higher failure rate for organs transplanted in adults from female donors to male recipients has been reported.
Gavaler, JS, Pillay, P, Starzl, TE, Van Thiel, DH   +3 more
core   +1 more source

Better 10‐Year Cerebrovascular Outcome After Transplant Than on Standard‐Care in Sickle Cell Anemia: DREPAGREFFE Trial

American Journal of Hematology, EarlyView.
ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin, Suzanne Verlhac, Elisabeth Ducros‐Miralles, Cécile Arnaud, Isabelle Genty, Marie Petras, Catherine Paillard, Gonzalo De Luna, Benoit Meunier, Isabelle Thuret, Annie Kamdem, Corinne Pondarré, Giovanna Cannas, Christelle Chantalat‐Auger, Nadia Firah, Sophie Pertuisel, Laure Joseph, Florence Missud, Mariane de Montalembert, Corinne Guitton, Claire Pluchart, Valentine Brousse, Monique Elmaleh, Vincent Gajdos, Emmanuella Leveillé, Ekaterina Belozertseva, Mabel Gaba, Catherine Poirot, Virginie Barraud‐Lange, Philippe Chadebech, France Pirenne, Myriam Bernaudin, Bénédicte Neven, Pierre Frange, Marie Angoso, Karima Yakouben, Bénédicte Bruno, Nathalie Dhédin, Jean‐Hugues Dalle, Regis Peffault Delatour, Camille Jung   +40 more
wiley   +1 more source

Nutrition and pubertal development

Indian Journal of Endocrinology and Metabolism, 2014
Nutrition is one of the most important factors affecting pubertal development. Puberty entails a progressive nonlinear process starting from prepubescent to full sexual maturity through the interaction and cooperation of biological, physical, and ...
Ashraf Soliman, Vincenzo De Sanctis, Rania Elalaily   +2 more
doaj   +1 more source

Juvenile granulosa cell tumor in a nine year old

Journal of Pediatric Surgery Case Reports, 2020
Pediatric granulosa cell tumors of the ovary are rare functional neoplasms causing secondary precocious puberty. The tumor possesses significant diagnostic challenge when occurs in a patient approaching puberty due to masking of symptoms.
Syed Waqas Ali, Nouman Nawaz Ali, M. Sajjad Ashraf, Muhammad Arif Mateen Khan, Muhammad Usman Tariq   +4 more
doaj   +1 more source

Complex Genetic Architecture in RASopathies: Constitutional PTPN11 and Mosaic RIT1 Pathogenic Variants Underlying Severe Noonan Syndrome With Adult‐Onset Acute Myeloid Leukemia

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan syndrome (NS) is a genetically heterogeneous disorder characterized by a broad spectrum of clinical features resulting from dysregulation of the RAS/MAPK pathway. Although complex genotypes are increasingly recognized in NS, cases harboring two distinct pathogenic variants in different NS genes remain extremely rare.
Francesco Prevedello, Dario Seif Ali, Chiara Piccolo, Chiara Rigon, Monica Forzan, Elena Tacchetto, Roberta Palmitessa, Davide Calosci, Leonardo Salviati, Carmela Gurrieri, Eva Trevisson   +10 more
wiley   +1 more source

The Role Of School Counselors To Helping Student in Puberty Through The Collaborative Paradigm

Enlighten, 2020
Adolescent is one of the stages in human life that is very critical, because it is a stage of transition from childhood to adulthood. At this stage a lot of changes occur in adolescents, such as physical, emotional and social changes.
Ramdani Ramdani, Tamama Rofiqah, Imalatul Khairat, Muhammad Putra Dinata Saragi, Randi Saputra   +4 more
doaj   +1 more source

Influence of HFD-induced precocious puberty on neurodevelopment in mice

Nutrition & Metabolism, 2021
Background Precocious puberty is frequently associated with obesity, which will lead to long-term effects, especially on growth and reproduction. However, the effect of precocious puberty on children's neurodevelopment is still unknown.
Tingbei Bo, Jing Wen, Wenting Gao, Liqiu Tang, Min Liu, Dehua Wang   +5 more
doaj   +1 more source

Long‐Term Follow Up of Two Patients With Variants in the Cluster 1031‐1159 of TRRAP Gene: Expanding the Phenotype of Developmental Delay With or Without Dysmorphic Facies and Autism

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The transformation/transcription domain‐associated protein (TRRAP) gene encodes a large multidomain protein, a member of the phosphatidylinositol 3‐kinase‐related kinase (PIKK) family. TRRAP is a component of the histone acetyltransferase (HAT) complex, and it plays an important role in gene transcription, DNA repair, and cell‐cycle regulation.
Roseli Maria Zechi‐Ceide, Vinicius Contrucci Dantas Segarra, Siulan Vendramini‐Pittoli, Henrique Regonaschi Serigatto, Luiza Virmond, Heloisa Marcelina da Cunha Palhares, Fernanda Jehee, Ana Cristina Victorino Krepischi, Carla Rosenberg, Carlos Henrique Paiva Grangeiro, Nancy Mizue Kokitsu‐Nakata   +10 more
wiley   +1 more source

Nonlinear growth generates age changes in the moments of the frequency distribution: the example of height in puberty [PDF]

, 2008
Higher moments of the frequency distribution of child height and weight change with age, particularly during puberty, though why is not known. Our aims were to confirm that height skewness and kurtosis change with age during puberty, to devise a model to
Cole, TJ, Cortina-Borja, M, Kelly, FP, Pan, HQ, Sandhu, J   +4 more
core