Substance P regulates puberty onset and fertility in the female mouse [PDF]
Puberty is a tightly regulated process that leads to reproductive capacity. Kiss1 neurons are crucial in this process by stimulating GnRH, yet how Kiss1 neurons are regulated remains unknown. Substance P (SP), an important neuropeptide in pain perception,
Carroll, R.S. +7 more
core +1 more source
Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis [PDF]
The initiation of mammalian puberty and the maintenance of female reproductive cycles are events controlled by hypothalamic neurons that secrete the decapeptide gonadotropin-releasing hormone (GnRH).
Sabine Heger +56 more
core +2 more sources
Chronic kidney diseases affect sex hormones, and thus it is now hypothesized abnormal puberty phenomenon in adolescents suffering renal failure. The primary study endpoint was to assess the frequency of disorders related to the clinical incidence of ...
Davood Amirkashani +2 more
doaj +1 more source
Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. [PDF]
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women that is comprised of two out of the following three features: hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries. In addition to infertility, many women
Arroyo, Pablo +4 more
core +2 more sources
The effects of estrogen induction therapy on pubertal presentations in turner syndrome patients
Objective: In this study, we investigated various pubertal presentations and progressions before and after estrogen induction therapy and the correlations with Turner syndrome karyotypes. Materials and methods: We reviewed the medical records of patients
Yi-Chen Lee +7 more
doaj +1 more source
Puberty process in children born from Assisted Reproductive Technologies: a review study [PDF]
Introduction: The quality of puberty can affect the sexual health and fertility of children. There is limited evidence about the risks associated with the use of assisted reproductive methods (ART) on the process of puberty.
Mitra Savabi esfahani +2 more
doaj +1 more source
Background It is well known that excess adiposity during childhood may influence pubertal development. However, the extent to which body compositions vary in throughout puberty in boys and girls is currently unknown.
Fang He +5 more
doaj +1 more source
Maternal pre-pregnancy obesity and timing of puberty in sons and daughters: a population-based cohort study. [PDF]
BackgroundIn many countries, an increased prevalence of obesity in pregnancy has coincided with a declining pubertal age. We aimed to explore the potential effect of maternal pre-pregnancy overweight and obesity on timing of puberty in sons and daughters.
Arah, Onyebuchi A +7 more
core +2 more sources
The relationship between HSP70 and level of leptin and luteinizing hormones in female rats exposed to chronic and acute heat stress [PDF]
The current search experiments designed to study the effect of chronic and acute heat stress on the relationship between HSP70, leptin and luteinizing hormones level in female rats.
Hiyam N. Matty, Ashwaq A. Hassan
doaj +1 more source
Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay [PDF]
Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Achermann, JC +12 more
core +1 more source

