Results 41 to 50 of about 414,762 (264)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Revista de Contabilidad: Spanish Accounting Review, 2005 La organización administrativa y contable de los mayores municipios españoles, a comienzos del XVII, es un tema que apenas ha sido abordado por los investigadores de la historia de la Contabilidad y del Derecho.
Francisco Mayordomo García-Chicote
doaj
Yearbook of Swiss Administrative Sciences, 2011 Zusammenfassung Eine Übersicht über die italienischen Rechtsvorschriften betreffend notleidende Kommunen wird präsentiert, um sowohl die Art der finanziellen Notlage als auch die Haltung der Zentralregierung gegenüber notleidenden italienischen Kommunen ...
Emma Capalbo +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Designing a Model for Demand Side Management in Electricity Sector Based on Collaborative Governance [PDF]
مدیریت دولتیObjective Demand Side Management (DSM) in electricity energy is a pivotal strategy for governments aiming to effectively control the timing and amount of energy consumption during critical periods of peak load.
Gholamreza kazemian +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
DEMONSTRAÇÃO DE RESULTADO ECONÔMICO: PERCEPÇÃO DO COMANDO DA AERONÁUTICA DO BRASIL [PDF]
RAE: Revista de Administração de Empresas, 2014 In 2010, a change in the Brazilian accounting regulatory framework introduced the Demonstração do Resultado Econômico (DRE) [Economic Income Statement] for the public sector, which seeks to compare the internal costs of production to market values ...
Delfina Rosa da Rocha Gomes +1 more
doaj
Contextual smart governance, a new approach to urban governance [PDF]
برنامهریزی توسعه شهری و منطقهایUrban governance approaches are undergoing significant transformation. Due to the increasing role of technology in urban functions, smart governance is recognized as an appropriate solution to address urban issues.
sahar zamani nezhad +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The Reputational Basis of Public Accountability [PDF]
Governance, 2015 This article proposes a reputation‐based approach to account for two core puzzles of accountability. The first is the misfit between behavioral predictions of the hegemonic political science framework for talking about accountability, namely, principal–agent, and empirical findings. The second puzzle is the unrivaled popularity of accountability, given
Busuioc, E.M., Lodge, M.
openaire +3 more sources