Results 131 to 140 of about 5,193,344 (310)
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Diversity and Public Goods: A Natural Experiment with Exogenous Residential Allocation [PDF]
This paper demonstrates the effects of ethnic and religious diversity on the quality of public spaces. Its identification strategy relies on the exogeneity of public housing allocations in France, and thereby eliminates the bias from endogenous sorting ...
Algan, Yann +2 more
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Composition and dynamics of the adult nasal microbiome
MicrobiomeBackground The nasal microbiome, a dynamic assemblage of commensals and opportunistic pathogens, is crucial to human health. Results Using cross-sectional data from 1,608 adults and longitudinal sampling of 149 individuals over 8–22 months, we identified
Cindy M. Liu +19 more
doaj +1 more source
Relationships between nongovernmental organizations and the main actors from their environment [PDF]
NGOs can continue defend their operational independence in evolutionary conditions that imply from their behalf an important vigilant activity. The financial prosperity of big NGOs owes a lot to their conversion to direct marketing techniques, from the ...
Ioan NICOLAE
core
The Politics of Public Health: A Response to Epstein [PDF]
, 2003 Conservatives are taking aim at the field of public health, targeting its efforts to understand and control environmental and social causes of disease. Richard Epstein and others contend that these efforts in fact undermine people’s health and well-being
Bloche, Maxwell Gregg +1 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Substructure and Boundary Modeling for Continuous Action Recognition [PDF]
, 2012 This paper introduces a probabilistic graphical model for continuous action recognition with two novel components: substructure transition model and discriminative boundary model.
Huang, Thomas +4 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source