Results 131 to 140 of about 14,820,986 (315)

Systemic pedagogy: A design for Action Researcher collective self-development

, 2015
How do Action Researchers, who often work alone, develop their practice? The Conference Intensive (CI) was designed to enable participants to inquire into their own practice, and observe and learn with a team of Action Researchers negotiating practice ...
Vaartjes, Vicki, Reedy, Riripeti, Goff, Susan, Colliver, Ross   +3 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Cuckoo – using action research to record oral history

, 2011
Objective: To describe use of the Action Research stages of Planning, Action and Reflection as a valuable framework for an artist when developing new work. Approach: Artists generally work intuitively in an Action Research model.
Liebzeit, Anna
core  

Composition and dynamics of the adult nasal microbiome

Microbiome
Background The nasal microbiome, a dynamic assemblage of commensals and opportunistic pathogens, is crucial to human health. Results Using cross-sectional data from 1,608 adults and longitudinal sampling of 149 individuals over 8–22 months, we identified
Cindy M. Liu, Lise Tornvig Erikstrup, Sofie M. Edslev, Daniel E. Park, Juan E. Salazar, Maliha Aziz, Amalie Katrine Rendboe, Tony Pham, Khoa Manh Dinh, Kelsey Roach, Abigail Onos, Edward Sung, Nathan O. Weber, Paal Skytt Andersen, Henrik Ullum, Robert Skov, Bruce A. Hungate, Marc Stegger, Christian Erikstrup, Lance B. Price   +19 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Using Action Research in Practice: Project and Knowledge Management Studies

, 2017
The aim of this paper is to describe a direct and personal account of the issues and challenges that occurred in three action research projects that were part of a doctoral research programme.
Duffield, Stephen Mark
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Intimate partner violence and postpartum healthcare access in Kenya: a cross-sectional study

BMC Pregnancy and Childbirth
Background Intimate partner violence (IPV) impacts physical health, mental health, and healthcare use. IPV during pregnancy, in particular, is associated with lower rates of antenatal care, but no studies have assessed the association between IPV and ...
Rebecca Woofter, John Mboya, Ginger Golub, May Sudhinaraset   +3 more
doaj   +1 more source