Results 91 to 100 of about 10,798,625 (391)

Global public policy, transnational policy communities, and their networks [PDF]

, 2008
Public policy has been a prisoner of the word "state." Yet, the state is reconfigured by globalization. Through "global public–private partnerships" and "transnational executive networks," new forms of authority are emerging through global and regional ...
Albert M., Alexander Cynthia, Arthurs Harry., Baltodano Andres Perez., Bourguignon Francois, Brutsch Christian, Bull Benedicte, Cerny Phil., Deacon Bob, Drache Daniel., Drori Gili, John W., Dye Thomas., Evans Mark, Grugel Jean, Gulrajani Nilima., Kaul Inge, Keck Margaret, Kettl Donald F., Krause Hansen Hans, Ladi Stella, Mbabazi Pamela, Nowotny Helga, Ottaway Marina., Reinicke Wolfgang, Reinicke Wolfgang H., Ronit Karsten, Sinclair Timothy., Slaughter Anne Marie., Soroos Marvin S., Stone Diane., Thakur Ramesh, True, Jacqueline, Weiss Thomas G., World Bank, Operations Evaluation Department, Wycherley R. E., Xu Yi-Chong   +35 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

The role(s) of accounting and performance measurement systems in contemporary public administration

, 2020
The spate of public sector reforms which have taken place in recent decades has triggered the development of a new body of research around public sector accounting and performance measurement both in public administration as well as in the (public sector)
I. Steccolini, Iris Saliterer, J. Guthrie   +2 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Reforming of public administration in Ukraine in the context of the European integration

Lex Portus, 2019
In this article the main approaches of reforming of public administration in Ukraine are designated on the basis of application of a system of general scientific and special methods of knowledge in the context of the European integration.
Nesterenko Kateryna , Bohatyrova Maryna
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

STRATEGIC PLANNING IN PUBLIC ADMINISTRATION [PDF]

In order for Romania to meet its new political and social expectations as an E.U. member, the Romanian Public Administration has to be reformed. Nationwide, Romanian Public Administration has to assure the same endowment for service quality.
Alina RAILEANU, Anca Gabriela TURTUREANU, Ioan BORDEAN   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

PUBLIC ADMINISTRATION REFORM IN ROMANIA [PDF]

When considering the change of the Romanian society, one cannot ignore the public administration system, the need for introducing a modern dimension in this system and for sharing the values of the European administrative space.
Berceanu Oana, Buziernescu Radu, Nanu Roxana   +2 more
core