Results 91 to 100 of about 10,255,049 (415)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Eurofound\u27s Definition of Central Public Administration [PDF]

, 2013
[Excerpt] Since Eurofound engaged in more systematic research on the public sector, defining central public administration has become a necessity. While there is a branch of research dedicated to employment and working conditions in the sector, linked ...
Biletta, Isabella, Cabrita, Jorge, Götzelmann, Christina   +2 more
core   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, Volume 19, Issue 5, Page 1493-1507, May 2025.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

THE PROBLEM OF THE USA PRIVATE BUSINESS PARTICIPATION IN THE SYSTEM OF PUBLIC ADMINISTRATION. THE EXXON MOBIL CORPORATION EXAMPLE

RUDN Journal of Public Administration, 2018
The subject of consideration of this article is the mechanism for the formation of public administration of the United States. The US public administration system is characterized by continuity in domestic and foreign policy over the past 70 years as a ...
Dariya Vladimirovna Stanis, Konstantin Petrovich Kurylev   +1 more
doaj   +1 more source

Expanding the Housing Stock for the East Side Neighborhood of Chicago Heights [PDF]

, 1980
https://opus.govst.edu/ippa/1023/thumbnail ...
Institute for Public Policy and Administration,
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

REGULATORY AND REGULATING DOCUMENTATION IN SCIENCE AND EDUCATION: PECULIARITIES OF LANGUAGE AND FORMULATION

RUDN Journal of Public Administration, 2018
The modern administrative system of the Russian Federation is characterized by an increasing number of regulatory aspects. This property is especially widespread in the sphere of science and education.
Grigoriy Arturovich Kliuchrev, Alexander Viktorovich Neverov   +1 more
doaj   +1 more source

Behavioral Public Administration

, 2020
Behavioral public administration is an interdisciplinary research field that studies public administration topics by connecting insights from public administration with psychology and, more broadly, the behavioral sciences. Behavioral public administration scholars study important public problems such as discrimination, corruption, and burnout. Various
openaire   +2 more sources

Wheeling Township: A Socio-Economic Demographic Fact Book [PDF]

, 1996
https://opus.govst.edu/ippa/1047/thumbnail ...
Institute for Public Policy and Administration,
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source