Results 111 to 120 of about 14,048,862 (292)

The Dynamics of Public Policy-Making in Public Administration: From Classical Management to the New Public Administration

Journal of Contemporary Governance and Public Policy
This article examines how public administration shapes policy-making. Scholarship typically treats Classical Management, Neo-Classical Management, and New Public Administration (NPA) as successive stages, while policy studies often analyse decision ...
Abdul Rahman, Septi Wulandari, Komang Ema Marsitadewi, Teresa Irmina Nangameka, Shelda Adriana Taimaris Rogi   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The influence of non-political organizations on the activities of formalized political institutions in contemporary Japan

RUDN Journal of Public Administration
The purpose of the research is to examine the mechanisms of influence of the South Korean Christian nationalist organization “Unification Church”2 in Japan. Particular attention is paid to its influence on the socio-political aspects of internal Japanese
Alexandra S. Roslyakova, Olga A. Ledovskaya   +1 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

The use of blockchain technology for preserving cultural heritage and its impact on political processes

RUDN Journal of Public Administration
One of the pressing issues in the modern world is the problem of trust in authority. Cultural heritage and the challenges associated with its acknowledgment and preservation often directly influence political processes both within countries and in ...
Denis A. Gromyko
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Public administration under populist rule : standing up against democratic backsliding [PDF]

Published online: 02 August 2023What happens to democratic administration when populists come to power? This article depicts the contours of the debate within the discipline of Public Administration (PA) about populist attempts to transform the state ...
BAUER, Michael W.
core   +1 more source

A model for prevocational training of specialists: managing the “Media class in Moscow schools” project as an example of implementing state and municipal education policy

RUDN Journal of Public Administration
The study presents an analysis of the development of pre-professional education in Moscow with an emphasis on the implementation of the Media Class in a Moscow School project, which has become an example of successful integration of media technologies ...
Andrey V. Sazonov, Alexandrina A. Svetlova, Sergey V. Morozov   +2 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Citizens’ Inclusion in Public Services: a Systematic Review of the Public Administration Literature and Reflection on Future Research Avenues [PDF]

Data Availability Statement: Data sharing not applicable—no new data generated.Despite a resurgence of interest in social equity, citizens' inclusion in public services has attracted limited attention in the public administration literature so far ...
Chang, S, Ileana, S, Licsandru, T, Meliou, E   +3 more
core   +1 more source