Results 121 to 130 of about 1,414,154 (297)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The Contracts of Public Administrations

Revista de la Facultad de Derecho de México, 2018
Practicamente no existe ningun aspecto de la teoria de los contratos que haya escapado a un analisis cuidadoso en terminos comparativos.  La renuencia tradicional de la ley administrativa a de verse obligada a cierta medida de homogeneizacion. Por lo tanto, es dificil explicar por que ningun tratado, libro o articulo extenso se ha dedicado a una ...
openaire   +3 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

The Dynamics of Public Policy-Making in Public Administration: From Classical Management to the New Public Administration

Journal of Contemporary Governance and Public Policy
This article examines how public administration shapes policy-making. Scholarship typically treats Classical Management, Neo-Classical Management, and New Public Administration (NPA) as successive stages, while policy studies often analyse decision ...
Abdul Rahman, Septi Wulandari, Komang Ema Marsitadewi, Teresa Irmina Nangameka, Shelda Adriana Taimaris Rogi   +4 more
doaj   +1 more source

Philosophy and Public Administration: Philosophy and Public Administration

, 2020
Philosophy and Public Administration provides a systematic and comprehensive introduction to the philosophical foundations of the study and practice of public administration. In this revised second edition, Edoardo Ongaro offers an accessible guide for improving public administration, exploring connections between basic ontological and epistemological ...
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

MAIN ACTORS OF THE ROMANIAN PUBLIC ADMINISTRATION REFORM [PDF]

This article is devoted to public administration reform and proposes a series of measures to strengthen the effectiveness of the reform process through the modification or creation of new institutional structures and procedures at the highest level.
Tudorel ANDREI, Alina PROFIROIU
core  

The influence of non-political organizations on the activities of formalized political institutions in contemporary Japan

RUDN Journal of Public Administration
The purpose of the research is to examine the mechanisms of influence of the South Korean Christian nationalist organization “Unification Church”2 in Japan. Particular attention is paid to its influence on the socio-political aspects of internal Japanese
Alexandra S. Roslyakova, Olga A. Ledovskaya   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source