Results 41 to 50 of about 7,419,101 (342)

The perception of public servants about the practice of the principles LIMPE: a study at the University of Brasilia

Economia & Região, 2021
The aim of this paper is to seek evidence on the perception of public servants of the University of Brasilia regarding the practice of explicit constitutional principles of public administration in the caput of article 37 of the Federal Constitution ...
Alisson Assis de Lima, Luiz Honorato da Silva Júnior   +1 more
doaj  

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Teaching in uncertain times: The future of public administration education

Teaching Public Administration, 2020
The outbreak of severe acute respiratory syndrome coronavirus (SARS-CoV-2), and its resulting coronavirus disease 19 (COVID-19), needs no introduction.
Bruce D. McDonald
semanticscholar   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Considerations on the Remuneration System of the Public Administration – an Analysis on Electoral Cycles and Scenarios Development [PDF]

Theoretical and Applied Economics, 2009
The paper aims to identify trends in the characteristics of the number of employees and the average salary in public administration in the last two election cycles in the period 2000-2008 compared with other sectors and proposes a series of three ...
Tudorel Andrei, Marius Profiroiu, Bogdan Oancea, Monica Nedelcu   +3 more
doaj   +1 more source

The role(s) of accounting and performance measurement systems in contemporary public administration

, 2020
The spate of public sector reforms which have taken place in recent decades has triggered the development of a new body of research around public sector accounting and performance measurement both in public administration as well as in the (public sector)
I. Steccolini, Iris Saliterer, J. Guthrie   +2 more
semanticscholar   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The Research of the Administrative Phenomenon Within the European Space from the Perspective of the Organisms Specialized in Professional Trading

EIRP Proceedings, 2011
The problematic of the continuous training, specialization and perfection of professional training of public servants and contractual personnel in the public administration has constituted the reason for which the European Commission sustained the ...
Gina Livioara Goga, Gabriel Gurita
doaj  

Cursos de Administração: a dimensão pública como sujeito excluído

Cadernos EBAPE.BR
Resumo:Este artigo analisa a presença dos conhecimentos abrangentes sobre administração pública na formação do administrador de empresas. Considera-se que a expansão do ensino da Administração, no Brasil, deu à formação universitária papel muito ...
Agatha Justen, Claudio Gurgel
doaj   +1 more source