Results 71 to 80 of about 10,255,049 (415)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

The support of the social entrepreneurship: Russian and world best practices

RUDN Journal of Public Administration, 2018
Social entrepreneurship is a new phenomenon in Russian practice. The article discusses the experience of social entrepreneurship in Russia and abroad, taking into account its diversity and research potential.
I V Lagun, S V Bogatyrev
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Public administration megacities in the context mechanisms of public administration

Aspekti Publìčnogo Upravlìnnâ, 2014
The article analyzes scientific research of public management of megacities in the context of governance mechanisms. Particular emphasis is placed on the correlation of theoretical and practical approaches to determine the effectiveness of public ...
R. A. Makhynia
doaj  

Women’s Political Participation in Jordan

RUDN Journal of Public Administration, 2020
Jordanian womens participation in public policy dates back to 1950s. However, political activism came to a halt in the period between 1956 and 1992. In 1992, the new Political Parties Law granted women the right to participate in political parties. Since
Mazen Hussien Faleh Hawamdeh, Ahmad Saher Ahmad Al-Qteishat   +1 more
doaj   +1 more source

The Contracts of Public Administrations

Revista de la Facultad de Derecho de México, 2018
Practicamente no existe ningun aspecto de la teoria de los contratos que haya escapado a un analisis cuidadoso en terminos comparativos.  La renuencia tradicional de la ley administrativa a de verse obligada a cierta medida de homogeneizacion. Por lo tanto, es dificil explicar por que ningun tratado, libro o articulo extenso se ha dedicado a una ...
openaire   +4 more sources

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

PUBLIC ADMINISTRATION AS STORYTELLING

Public Administration, 2011
I’ll tell you a storyAbout Jack a Nory,And now my story's begun;I’ll tell you anotherOf Jack and his brother,And now my story is done.[Anon] A great writer of fiction both creates a new, unique, individual world – through acts of imagination, through language that feels inevitable, through commanding forms – and responds to a world, the world the ...
openaire   +3 more sources