Results 81 to 90 of about 10,277,087 (391)

Public administration, public leadership and the construction of public value in the age of the algorithm and ‘big data’

open access: yesPublic Administration, 2018
Public administration scholarship has to a significant degree neglected technological change. The age of the algorithm and ‘big data’ is throwing up new challenges for public leadership, which are already being confronted by public leaders in different ...
L. Andrews
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Domestic violence in Australia: interim report [PDF]

open access: yes
One in three Australian women have experienced physical violence since the age of 15 and almost one in five have experienced sexual violence.  A study of Victorian women demonstrated that domestic violence is the leading preventable contributor to ...
Senate Finance and Public Administration References Committee
core  

The Correlation between Enrollment Status and Graduation Rates of Master of Public Administration Programs [PDF]

open access: yes, 2018
Statement of the Problem The Network of Schools of Public Policy, Affairs and Administration (NASPAA) is an international association of universities and colleges that grant professional master’s degrees in public policy, affairs and administration.
Ferrer, Jasmine Lorraine
core   +1 more source

THE NEW SYSTEM OF QUALIFICATION REQUIREMENTS FOR PERSONNEL CHANGES THE REQUIREMENTS FOR EMPLOYEES OF PERSONNEL SERVICES

open access: yesRUDN Journal of Public Administration, 2018
The article is devoted to the functional changes of the modern human resources departments, to the comparison of special elements of the system of human resources management in soviet period and nowadays, standardization of the qualification requrements ...
Anna Aleksandrovna Sokolova
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Foreign experience in the implementation of state financial control in the sphere of capital construction

open access: yesRUDN Journal of Public Administration, 2019
This article is devoted to the peculiarities of the implementation of state financial control in the construction sphere by foreign control and accounting bodies.
Rinat Gabdelhaevich Ibragimov
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

MDL as Public Administration

open access: yesMichigan Law Review, 2019
From the Deepwater Horizon disaster to the opioid crisis, multidistrict litigation—or simply MDL—has become the preeminent forum for devising solutions to the most difficult problems in the federal courts. MDL works by refusing to follow a regular procedural playbook. Its solutions are case specific, evolving, and ad hoc. This very flexibility, however,
openaire   +3 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

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