Results 81 to 90 of about 10,277,087 (391)
Public administration scholarship has to a significant degree neglected technological change. The age of the algorithm and ‘big data’ is throwing up new challenges for public leadership, which are already being confronted by public leaders in different ...
L. Andrews
semanticscholar +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Domestic violence in Australia: interim report [PDF]
One in three Australian women have experienced physical violence since the age of 15 and almost one in five have experienced sexual violence. A study of Victorian women demonstrated that domestic violence is the leading preventable contributor to ...
Senate Finance and Public Administration References Committee
core
The Correlation between Enrollment Status and Graduation Rates of Master of Public Administration Programs [PDF]
Statement of the Problem The Network of Schools of Public Policy, Affairs and Administration (NASPAA) is an international association of universities and colleges that grant professional master’s degrees in public policy, affairs and administration.
Ferrer, Jasmine Lorraine
core +1 more source
The article is devoted to the functional changes of the modern human resources departments, to the comparison of special elements of the system of human resources management in soviet period and nowadays, standardization of the qualification requrements ...
Anna Aleksandrovna Sokolova
doaj +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
This article is devoted to the peculiarities of the implementation of state financial control in the construction sphere by foreign control and accounting bodies.
Rinat Gabdelhaevich Ibragimov
doaj +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
From the Deepwater Horizon disaster to the opioid crisis, multidistrict litigation—or simply MDL—has become the preeminent forum for devising solutions to the most difficult problems in the federal courts. MDL works by refusing to follow a regular procedural playbook. Its solutions are case specific, evolving, and ad hoc. This very flexibility, however,
openaire +3 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source